Clean scientific graphic showing NMN moving through the NMNAT salvage pathway toward NAD+ and an illuminated mitochondrion, with a precise blue laboratory aesthetic

Macro close-up of fine white NMN powder in a measuring scoop beside the open Pure NMN jar and quality-testing paperwork, framed on a clean blue-and-white laboratory surface

Overhead product demonstration of one measured scoop of NMN powder dissolving into a clear glass of water during a simple morning routine, with the open jar nearby

Tight studio close-up of the Pure NMN jar label and supplement facts panel showing 500 mg per serving, with a level measuring scoop in the foreground

Science-forward macro image of illuminated molecular structures and cellular pathways representing NAD+ support for sirtuins, PARPs, and everyday cellular maintenance

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NMN Two Scoops Daily Short

NMN Two Scoops Daily Short - The Wellness Guru - 5 Reasons to Choose Pure NMN

Frequently Asked Questions

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Like how Apigenin helps sleep and digestion, also nice new design of the container!

5 Stars

David

Renue by Science knocks it out of the ballpark AGAIN!! Been going this company for yrs now and this particular product blends in beautifully w/ my NAD and NMN!! Since taking this my sleep has improved even more!! I’m 55 yrs old and my overall health and Wellness is Everything to me!! Cannot recommend enough! 
— Teresa 
Arizona 

Phenomenal! ESP for SLEEP 😴 

Teresa M.

Renue by Science provides exceptional products and backs the supplement line up with peerless customer service. As for the Apigenin specifically it’s been a game changer for my sleep quality. 

Without peer

Charles C. H. S.

I am confident that the supplement will show its effectiveness in due time , since I started a few days ago , it’s too early to say.

Apigenin

Manuel O.

I've been taking this for the last year at least. I take it right before bed and it helps me sleep like nothing else. It does not impact my waking the next morning or my personality/mood the next day. The fact that it decreases CD38 and has other benefits is just awesome!

Great All Around

Thomas H.

Great help for a good night sleep and a fresh start in the morning.

Good night

Juan Z.

I take like 8 of these a day and it made my hairline regrow to where it was in highschool, also makes it easy to take naps/fall asleep at night.

I take like 8 of these a day and it made my hairline regrow to where it was in highschool

David C.

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I have noticed a substantial difference with nasal spray versus the powder.

Darren

モヤモヤして頭がスッキリしない、頭が働かない、体がだるい。そんな不調を一気に解消してくれる点鼻スプレーです。点鼻スプレーは錠剤を飲むより効果が出るのが早く、毎日気分良く効率的に動けるので手放せません！毎日、片側に１プッシュずつなので持ちもいいです。

頭がクリアになり、活力が湧きます！

雅子 長.

Donald

Have been on the nasal delivery of nad.  It is way to use and I spray 2x per day.  Hella with focus and gives me steady energy. 

Solid dose of NAD 

Peter A.

The product burns but I get through it every morning. It’s too soon to say if I see any effects.

Too soon to tell

Kasey L.

Daniel H.

I don’t usually write reviews, but this product has honestly impressed me enough that I had to. My mom and I started using this NAD peptide at the same time, and we’ve both noticed a remarkable difference.

The biggest change has been our energy. Instead of feeling like we have to push through the day, we actually have steady, natural energy without feeling jittery. What surprised me even more was the mental clarity. I feel more focused, my mind feels sharper, and it’s much easier to stay on task instead of feeling mentally foggy.

It’s rare for both of us to have such a positive experience with the same product, but that’s exactly what happened. Everyone’s experience will be different, of course, but for us this has been one of the best supplements we’ve tried. We’ll definitely be purchasing it again.

    Life-Changing Energy and Mental Clarity

Elizabeth G.

I have used NAD+ spray, NMN, and NR for several months. My hair grows faster & looks better. This was noted in a recent study in Japan. Andrew Huberman also has noticed this. My energy level is excellent.

NAD+ Complete Nasal Spray

Renue Blue Face Serum

Trans-Resveratrol

Complete Your Daily Longevity Stack

Linda

like it, notice a difference in clarity already

Timothy

Warren

Great flavor and smooth texture! I am so impressed by how good this tastes. The powder is incredibly fine and definitely not grainy like other brands I’ve tried. Taking my 2 scoops a day is super easy because it dissolves completely and tastes great.

Absolutely love this powder!

Popovich P.

Danny

I started in January 2026, love the results! I feel great and look  younger. My co- workers all are on it now because they see my improvement. That’s 6 people, which makes me happy to pass on such a great product.

Great product

Sheila O.

Exactly what I ordered and in a timely manner!

Joshua

Cheaper than hydration  IV treatments. I’m on my second bottle. Results are fantastic. My energy is even though through the roof. Focus and clarity with an amazing night sleep every time..

Great pure NMN product. 

Highly micronised, pure NMN powder. Odourless and tasteless. I put it in my coffee in the morning.

This is the best NMN we’ve tried so far. Actually ordered when the other brand we were using was out of stock. Glad we changed and will be staying with the Renue by Science brand going forward. Also great value for money by volume! Highly recommend.

NMN Pure Powder

Drucilla

Big improvement on energy and deterioration of her muscles in back legs. This is an excellent product especially as your dog gets older. Highly recommended product. You will see changes around 20 days in approximately and you will probably really notice it by the 40day mark

Great for older dogs and those approaching 

Samantha B.

my mini schnauzer was having a hard time moving around.. been on this a couple of weeks and he is back moving around all now. Just trying to keep him alive. Tried lots of stuff but this seems to be working best for him now… had him on galliprant, wuffles, cosquin, adequan, LIbera, etc… 

Helps my 18 year old mini schnauzer… just trying to keep him alive

Ken H.

My beagle loves these chews and her activity is like that of a puppy! She is well toned and muscular.  Even the Vet was impressed with her muscles. I attribute a lot to these chews.

Blossom, my beagle loves her longevity chews!

Sharon S.

Daphne

Fast delivery  and lots of good people products too! . At 13.5 years old is holding his own. I take NMN so it’s only fair he gets some too.

Nine year old female Boxer with advancing spinal neurological disease whose mobility seems to have stabilized since taking increased dosage of NMN chews.

This is my 3rd purchased the MNM supplement, and I couldn't be happier with the results! From the first week, I noticed a significant boost in his energy, which has made a big difference in his daily routine. He doesn't like the taste so a honey coated.

What I appreciate most is how it supports not just physical health but also mental clarity. I feel Andy is more active through out the day 

Overall, I highly recommend MNM to anyone looking to enhance their beloved dog's wellness journey. It's become an additional supplement in his routine, and I’m excited to continue seeing the benefits!

Our 13 year old Chihuahua has been enjoying the NMN for over 6 months, now. He has SO much energy and vitality! You'd think he was a puppy, not a senior!

I have a 10 year old chihuahua mixed. I started using this supplement combined with healthy home cooked diet, she is definitely healthier. 1 cube per day mixed with cooked food at night. I am a satisfied customer of Renue for several years for my daily maintenance.

Thank you for making pet MNM available!!!

My little one was 12 when I started her on nmn. Her life span for her breed is 10-12. She was laying around. Couldn’t jump up on my bed anymore. Just sad to see her decline. Then I started her on NMN. What could we lose. Her health and quality of life was slowing down. Then I started her on NMN. She has been on these for about a year and looks and acts like a puppy again. The Vet couldn’t believe her own eyes.

Very good 👍 she can jump on my bed again 😀

PET NMN Longevity Chews for Dogs

NAD+ Complete

Spermidine

NR Powder Smooth Taste Blend

NMN Liposomal Capsules

TMG Methylation Essentials

Customers generally report improved energy, better recovery, and convenience from the multi-supplement NAD+ protocol, with strong praise for the bundled format and perceived value. A smaller set of reviews reports little noticeable benefit or unwanted effects such as grogginess, restless sleep, or stomach upset, especially around the PM supplement. Customers also note the protocol’s ease of use and packaging, along with occasional concerns about whether the results justify continued purchase.

All rounder enery booster. Have noticed strength gains in gym since using!!

I feel much better since using this protocol!

After first week my energy has increased.

I can definitely tell a difference in my energy levels.

Customers say the protocol increases energy, vitality, and day-to-day stamina, often noting a noticeable lift after consistent use.

I love how much simpler it is to have most of what I need together in 4 bottles.

Love how they put these together as one NAD+ protocol.

love the way it is set up easy for her to take

I like the idea of liposomes, precursors and co-factors included in the products.

Customers say the bundled protocol is easy to take, simpler than managing separate supplements, and convenient for daily use.

I like that there is also a sleep pill! My Oura sleep score has been improving

I have more energy throughout the day and sleep better.

The melatonin in the PM supplement was the only thing that worked for falling asleep

I wake groggy and feel "off" for a few hours, not energetic.

Customers report that the night supplement helps sleep for some but also causes grogginess, restless sleep, or vivid dreaming for others.

I feel younger, more vibrant and energized than in years.

there has been a subtle improvement in my energy.

better energy and mental focus taking the protocol.

noticeable difference in energy and ... clarity and focus I hadn’t realized I was missing before.

NR, etc. have diminished a frightening brain-fog

Customers say the protocol improves mental focus, clarity, and brain fog, making thinking feel sharper and more steady.

the difference is when rest is poor or overworked, I rebound faster and feel better.

Customers say the protocol helps with workout recovery, morning stiffness, knee pain, and bouncing back after being overworked.

All rounder enery booster. Have noticed strength gains in gym since using!! 

Energy booster

S H.

Best Nad bundle is have used inexpensive worth its weight in gold between the Lipsomal tech to deliver the product to your blood and the way it relieves the CD38 inflammation it's worth every penny it does exactly as the product claims


Total NAD is TOTALLY RAD

Eric S.

I love how much simpler it is to have most of what I need together in 4 bottles. I have a son with Down syndrome taking this too. It’s so much easier for him. I’m trying to keep Alzheimer’s away and it’s working!

It’s great to have our “Stack” in 4 bottles 

Catherine S.

I started Total NAD+ Protocol about 8 month's ago after taking control of everything that relates to my health. The 4 part package of supplement's have energized a total transformation and I feel younger, more vibrant and energized than in years. Aging does not have to mean feeling old and sluggish. Yes I would and do recommend this product! It works!!!

Total NAD+ Protocol Works!!!

Randy

I have been using the NAD+ Restoration Protocol for one year.  My energy level has increased greatly. Morning stiffness is gone.  My knee pain is a thing of the past.  I’m so happy I tried this!

Best gift for myself

Jonna P.

Hi, Not sure what happens w/ my body and the Restore supplements. I wake groggy and feel "off" for a few hours, not energetic. So I stopped taking. I have a full unopened, sealed bottle from the second shipment and most of the first bottle from the initial shipment. For future buys I'll buy separately the NAD, Senolytique and Energizer.

Everything But Restore PM

Marcia D.

I like the combination but haven’t received the product yet!! As you should know, Canada’s postal service is on strike, has been for 22 days now or so. So hopefully you DIDN’T send it by mail! 🤔

4 Stars

John M.

Love how they put these together as one NAD+ protocol

M U.

Alexander

Took these consistently and did not notice a change in energy and/or vitality. The melatonin in the PM supplement was the only thing that worked for falling asleep but not staying asleep.

No difference noted

Esmeralda

I bought a 2-month supply. I'm 3 weeks into it and they asked me to review. As of right now I'm not certain. I think I feel the effects subtly I don't know. I'm just hoping that it's working lol

I believe, based on a lot of careful research, that ‘Renue by Science’ products are at the ‘cutting edge’ of longevity supplements. I feel healthy and energized by taking them.

Total NAD+ Restoration Protocol

Trans-Resveratrol Pure Powder

Berberine

CoQ10

The 24-Hour Skin Cycle

Love the simplicity and the concentration means a little goes a very long way. Living in a new higher altitude & dryer climate Renue’s Blue skincare line has been a real game changer. 

Highly recommend

Dana C.

I recommend 

Arman G.

Still early days, so will see how it goes, seeing its works under the skin it will probably take a while to notice

Jennifer

I'm always skeptical when products claim great results but I'm  pleasantly surprised with the RenuebyScience Blue Face Serum! Feels great on my skin & absorbs fast. It really feels great after a red light face treatment.

Feels great on my skin

Annette L.

Absolutely love the formula, texture and scent of this serum! It is packed full of actives and ohhh so good! My skin is loving this right from the start and improving with each use of this RENUE blue face serum! 

Fantastic serum!

Kerry B.

Renue's face serum seems to be pretty effective at improving the health of your skin. I've used Ageless and Particle and I find Renue to be slightly better. Only negative comments is it's a bit watery and unless on sale more expensive than the others mentioned. 

Effective at reducing wrinkles and improving skin tone

Richard S.

I have actually seen a difference using this product- something I can't say for every product I try.  I found it on Tik Tok at discount or I probably wouldn't have tried it but I have to say wow, it works.  I used it before red light and every evening as well.  Works fine with tret and vitamin c.  I had an issue with the pump breaking off and contacted customer service and they replaced it right away.  

Thought I'd give it a try and I love it!

Kimberly M.

The serum is a dull green, different from my last bottle of formula in color by at least one shade. Its more greenish. Its my experience that product turns this shade with age.

3 Stars

Tegan

Dr. Mercola use to carry this, I get most of my supplements from him, have since 2015. This was missing in my stack, and I was not about to buy just any, so this is why I ordered yours, as it stood out being liposomal, which helps with your body using it. I have a health story, but will not go on about this at this time. I am with doctors at the Cleveland Clonic, and Mercy Hospital in Buffalo, NY, both are taking very good care of me. Happy to be a customer of yours, and for many more. THANK-YOU

needed for heart health

Martha C.

RECEPCION

Alan I.

Supplements

Yogev D.

Me encantó estoy muy emocionada 

Deysi C.

Have been using this product for a couple of years now. As a type 2 diabetic on insulin I SEE the difference it makes in my reporting.  Along with berberine, it is a constant balance I truly enjoy. Great product.

Five reasons cellular energy starts with NAD⁺ support.

NMN enters the pathway your body uses to produce NAD⁺.

A focused NMN formula backed by independent testing.

One measured scoop fits into the way you already start your day.

Every full scoop provides 500 mg of NMN.

NAD⁺ supports enzymes involved in everyday cellular upkeep.

A clearer standard for daily NMN.

Support NAD⁺ with a routine built for consistency.

Customer reviews

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Five reasons cellular energy starts with NAD+ support.

NMN enters the pathway your body uses to produce NAD+.