Category Archives: Featured

Does NR cause Cancer? Response to recent article

  A recent article in sciencedaily.com took some research out of context and wrote a [...]

NMN Clinical Studies (In Humans)

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FDA Moves to Stop Sales of NMN Supplements

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New Research with NMN by IV Shows Much Stronger Effect Than Oral Supplementation

There are now 12 studies published to date in humans with NMN supplementation. The previous [...]

Inhibition of CD38 increases NAD+ levels, extends life and healthspan in mice

CD38 increases as we age, driving down NAD+ levels CD38 is an enzyme that responds [...]

NMN triples NAD+ levels in humans

(Pencina et al., 2022 | The Journals of Gerontology) NMN doses of 1,000 mg taken [...]

NMN or NR – Which is better?

There has been few, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) [...]

Why Dr. Sinclair takes NMN instead of NR

There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) [...]

Bacteria in Gastrointestional Tract Metabolize NMN and Impact NAD+ Metabolome

This recently published research by Drs. Lindsay Wu, David Sinclair and others examined the pathways [...]

Why TOO MUCH NMN or NR is bad, and what you can do about it

If not protected, NMN and NR supplements are almost entirely degraded to NAM (Nicotinamide) before [...]

NAD+ for Metabolism and Brain, NMN for the body?

Do NMN and NAD⁺ have different effects on the body? Researchers use supplementation with NMN, [...]

First Randomized Clinical Trial: NMN increases muscle insulin sensitivity in prediabetic women

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women, Science, April 22, 2021 NAD+ is [...]

CD73 utilization shows importance of NMN to restore NAD+

This recent study found that in endothelial cells, the extracellular conversion of NMN to NR [...]

NAD+ is the Transport Molecule Used by the Body, Not Nicotinamide Riboside

Restoring NAD+ levels in older animals and humans is at the center of efforts to [...]

Sublingual delivery of NAD+ boosters

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What is NAD+?

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How NAD+ Boosts ATP and What it Means for Health and Aging

Much of the attention on the benefits of restoring NAD+ levels focus on its role [...]

1st NMN Human Study Demonstrates Safety and Faster Utilization than NR

The first study of NMN in humans was just published. https://www.jstage.jst.go.jp/…/advpub_EJ19-03…/_pdf/-char/en This japanese study looked [...]

NAD+ IV increases NAD+ levels in blood plasma 400% in humans

This study was just published that documented changes in plasma and urine levels of NAD+ [...]

Scientists discover SLC12a8 pathway used by NMN to restore NAD+ levels

Yes, NMN can cross the cell membrane intact This research was just published that found [...]

NMN product shows increased endurance and new blood vessel growth in mice

This new research, published March 22 in Cell, identifies the key cellular mechanisms behind vascular aging [...]

Exogenous NAD+ Increases Metabolism

Effects of Chronic NAD Supplementation on Energy Metabolism and Diurnal Rhythm in Obese Mice In [...]

NAD+ Supplements Regulate Energy Metabolism via the Hypothalamus

Exogenous nicotinamide adenine dinucleotide regulates energy metabolism via hypothalamic Connexin 43. There are some very [...]