{"title":"NMN Products","description":"","products":[{"product_id":"lipo-nmn-powdered-liposomal-nmn2","title":"NMN Liposomal Capsules","description":"\u003cp\u003eLIPO NMN features our proprietary, powder-based liposomes that protect NMN from digestive enzymes \u0026amp; carry it into the bloodstream for targeted systemic delivery.\u003c\/p\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491517915394,"sku":"656165996568","price":64.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/2026-04-16-RENUE-LIPO-NMN-1b.webp?v=1779158145"},{"product_id":"pure-powder-100-grams","title":"NMN Pure Powder","description":"\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: Product Comparison\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=267190\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=253181\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=267190\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 100%;\"\u003eNAD+ products have very poor bioavailability unless a delivery method is used that can protect the ingredient from digestion. When taken in regular capsules, less than 10% of NMN or NR make it to the bloodstream intact.\u003cbr\u003e\n\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 100%;\"\u003eTo address this problem, in 2016 we pioneered Sublingual delivery of NMN, and since then have advanced the industry further with Intranasal, Transdermal, and Liposomal NMN products.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 100%;\"\u003eHere we compare each of these, highlighting their unique strengths to help you decide which product is right for you.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"aligncenter wp-image-267216 size-full\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Chart-NMN-Product-Comparison2b.png\" alt=\"\" width=\"915\" height=\"846\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e* These assessments are relative. For example, ALL our products provide much greater bioavailability than standard capsules (which we do not offer), but we highlight liposomal delivery as it is more bioavailable than sublingual. All forms get a checkmark for \"Improved energy\" as they are nearly equal. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eConvenience\/Portability\u003c\/strong\u003e\u003c\/span\u003e - This is ideal for those who want the ability to take NMN with them throughout the day. Our sublingual tablets, LIPO capsules, and nasal spray are ideal for those who are on the go and who like to take NMN at different intervals throughout the day.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003e\u003cstrong\u003eFast Acting\u003c\/strong\u003e \u003c\/strong\u003e\u003c\/span\u003e - If fast acting is important to you, then we recommend our sublingual powder, tablets, or nasal spray as they bypass digestion. They can provide rapid absorption and reach systemic circulation for a noticable effect in minutes. So whether it's before a quick workout or you need to quickly focus on mental tasks, these products can give you a quick boost when you need it most.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eLong Lasting\u003c\/strong\u003e\u003c\/span\u003e - LIPO NMN lasts longer in the body than our other NMN products. Liposomes protect the active ingredients from digestion and release slowly in the bloodstream up to 24 hours.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eFastest Cognitive Effect\u003c\/strong\u003e\u003c\/span\u003e- The sublingual powder has a very fast effect on physical energy, but the intranasal spray has a much stronger impact on improved cognition (the relief of \"brain fog\").\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eImproved Energy\u003c\/strong\u003e\u003c\/span\u003e- Sublingual delivery is much faster acting and the energy boost is more quickly noticed, but the most common report from users of all NAD+ boosters is increased energy.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eEasiest to Take\u003c\/strong\u003e \u003c\/span\u003e - Some people have trouble swallowing pills or applying powder under the tongue. For those people, LSG NMN is easier because it comes in an easy to apply liquid gel.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eBest Bioavailability\u003c\/strong\u003e \u003c\/span\u003e - Approximately 30% of NMN taken sublingually gets absorbed directly into the bloodstream, while the rest passes through the GI tract and gets broken down into less effective nicotinamide. However liposomal delivery avoids degradation in the GI tract entirely, meaning far more NMN is delivered to the tissues intact.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eBest Cost per Milligram\u003c\/strong\u003e \u003c\/span\u003e - The NMN product with the best price is our sublingual powder as there is very little added cost for processing. Tablets are next. Manufacturing of Liposomes takes the most time and expensive machinery, so cost the most per Milligram.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eBest Overall Value\u003c\/strong\u003e \u003c\/span\u003e - The best overall value is the product which is best in price combined with best bioavailability. Bioavailability is how much of the product actually makes it to the cells intact. For example, our LIPO capsules cost more per milligram to manufacture, but are 3 to 5 times more bioavailable than sublingual products, so are much more cost effective.\u003c\/p\u003e\n\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: fda disclaimer\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=102875\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=253181\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=102875\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"row align-center\" id=\"row-1045449650\"\u003e\n\u003cdiv id=\"col-2124180850\" class=\"col medium-11 small-12 large-11\"\u003e\n\u003cdiv class=\"col-inner text-center\"\u003e\n\u003cdiv class=\"best_price\" style=\"padding: 10px 0 10px 0;\"\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThese statements have not been evaluated by the Food and Drug Administration. \u003c\/span\u003e\u003c\/center\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/span\u003e\u003c\/center\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-2124180850 \u003e .col-inner {\n  padding: 0px 50px 0px 50px;\n  margin: 0px 0px 0px 0px;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491519750402,"sku":"850055685192","price":54.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nmn-pure-powder_front_v1.png?v=1775861562"},{"product_id":"pet-nmn-longevity-dog-chews","title":"PET NMN Longevity Chews for Dogs","description":"\u003ch3\u003e\u003cspan style=\"color: #7384a0;\"\u003eNMN Longevity Chews for Dogs\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eDogs age faster than we do. We teamed up with experts in the longevity field and top veterinarians to create pet supplements designed to provide your pets with high quality NMN.\u003c\/p\u003e\n\u003cp\u003eOver the past few years, we’ve heard from hundreds of customers who believe their pets are benefiting from NMN.\u003c\/p\u003e\n\u003cp\u003eOur cold extrusion soft chews are carefully processed using very low temperatures to preserve maximum nutrient potency without using heat, water, or gumming agents.\u003c\/p\u003e\n\u003ch3\u003e\u003cspan style=\"color: #7384a0;\"\u003eSuggested Daily Use\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eUp to 40 lbs. - 1 chew daily\u003cbr\u003e41-80 lbs. - 2 chews daily\u003cbr\u003e80+ lbs. - 3 chews daily\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: fda disclaimer\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=102875\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=253181\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=102875\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"row align-center\"\u003e\n\u003cdiv class=\"col medium-11 small-12 large-11\"\u003e\n\u003cdiv class=\"col-inner text-center\"\u003e\n\u003cdiv class=\"best_price\" style=\"padding: 10px 0 10px 0;\"\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThese statements have not been evaluated by the Food and Drug Administration. \u003c\/span\u003e\u003c\/center\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/span\u003e\u003c\/center\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-1374828299 \u003e .col-inner {\n  padding: 0px 50px 0px 50px;\n  margin: 0px 0px 0px 0px;\n}\n\u003c\/style\u003e\n\u003cdiv class=\"row align-center\" id=\"row-345391971\"\u003e\n\u003cdiv id=\"col-1374828299\" class=\"col medium-11 small-12 large-11\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491519848706,"sku":"850055685307","price":34.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/pet-nmn-longevity-chews-for-dogs_unclassified_v1.png?v=1774942185"},{"product_id":"nmn-lipo-gel-sublingual","title":"NMN Resveratrol Gel","description":"\u003cp\u003eNMN with Resveratrol LIPO Gel is designed to support cellular vitality and overall well-being.\u003c\/p\u003e\n\u003cp\u003e2 pumps provide ▸240 mg liposomal NMN ▸40 mg liposomal Trans-Resveratrol\u003c\/p\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491520045314,"sku":"656165996414","price":63.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nmn-resveratrol-gel_front_v1.png?v=1774942068"},{"product_id":"pure-nad-nasal-spray-10-grams-pure-nicotinamide-adenine-dinucleotide-nad-new","title":"NAD+ Complete Nasal Spray","description":"\u003cp\u003eIf you’re looking for a convenient on-the-go product, our NAD+ nasal spray is the perfect complement to your main NAD+ supplements.\u003c\/p\u003e\n\u003cp\u003eThe NAD+ nasal spray provides targeted delivery, focusing on the brain, rather than widespread systemic circulation. It’s designed to have a stronger effect on cognition and brain fog than all other delivery methods.†\u003c\/p\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491520602370,"sku":"850055685215","price":59.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nad-complete-nasal-spray_front_v1.png?v=1774942028"},{"product_id":"lipo-nad-complete-powdered-liposomal","title":"NAD+ Complete","description":"\u003cp\u003eLIPO NAD⁺ Complete is a powerful 4-in-1 NAD⁺ booster, featuring our proprietary powder-based liposomes that protect NAD⁺, NMN, NR, \u0026amp; Trigonelline from digestive enzymes and carry them into the bloodstream for targeted systemic delivery.\u003c\/p\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491520700674,"sku":"656165996551","price":84.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nad-complete_front_v1.png?v=1776385221"},{"product_id":"pet-nmn-longevity-cat-chews","title":"PET NMN Longevity Chews for Cats","description":"\u003ch3\u003e\u003cspan style=\"color: #7384a0;\"\u003eNMN Longevity Chews for Cats\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eCats age faster than we do. We teamed up with experts in the longevity field and top veterinarians to create pet supplements designed to provide your pets with high quality NMN.\u003c\/p\u003e\n\u003cp\u003eOver the past few years, we’ve heard from hundreds of customers who believe their pets are benefiting from NMN.\u003c\/p\u003e\n\u003cp\u003eOur cold extrusion soft chews are carefully processed using very low temperatures to preserve maximum nutrient potency without using heat, water, or gumming agents.\u003c\/p\u003e\n\u003ch3\u003e\u003cspan style=\"color: #7384a0;\"\u003eSuggested Daily Use\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eUp to 10 lbs. - 1 chew daily\u003cbr\u003e10+ lbs. - 2 chews daily\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: fda disclaimer\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=102875\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=253181\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=102875\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"row align-center\"\u003e\n\u003cdiv class=\"col medium-11 small-12 large-11\"\u003e\n\u003cdiv class=\"col-inner text-center\"\u003e\n\u003cdiv class=\"best_price\" style=\"padding: 10px 0 10px 0;\"\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThese statements have not been evaluated by the Food and Drug Administration. \u003c\/span\u003e\u003c\/center\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/span\u003e\u003c\/center\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-1819438697 \u003e .col-inner {\n  padding: 0px 50px 0px 50px;\n  margin: 0px 0px 0px 0px;\n}\n\u003c\/style\u003e\n\u003cdiv class=\"row align-center\" id=\"row-1877117292\"\u003e\n\u003cdiv id=\"col-1819438697\" class=\"col medium-11 small-12 large-11\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491520897282,"sku":"656165996841","price":34.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/pet-nmn-longevity-chews-for-cats_front_v1.png?v=1774942170"},{"product_id":"nmns-240-ct-sublingual-tablets-2","title":"NMNs Fast Dissolve Tabs","description":"\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: Product Comparison\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=267190\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=253181\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=267190\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 100%;\"\u003eNAD+ products have very poor bioavailability unless a delivery method is used that can protect the ingredient from digestion. When taken in regular capsules, less than 10% of NMN or NR make it to the bloodstream intact.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 100%;\"\u003eTo address this problem, in 2016 we pioneered Sublingual delivery of NMN, and since then have advanced the industry further with Intranasal, Transdermal, and Liposomal NMN products.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 100%;\"\u003eHere we compare each of these, highlighting their unique strengths to help you decide which product is right for you.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"aligncenter wp-image-267216 size-full\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Chart-NMN-Product-Comparison2b.png\" alt=\"\" width=\"915\" height=\"846\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e* These assessments are relative. For example, ALL our products provide much greater bioavailability than standard capsules (which we do not offer), but we highlight liposomal delivery as it is more bioavailable than sublingual. All forms get a checkmark for \"Improved energy\" as they are nearly equal. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eConvenience\/Portability\u003c\/strong\u003e\u003c\/span\u003e - This is ideal for those who want the ability to take NMN with them throughout the day. Our sublingual tablets, LIPO capsules, and nasal spray are ideal for those who are on the go and who like to take NMN at different intervals throughout the day.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003e\u003cstrong\u003eFast Acting\u003c\/strong\u003e \u003c\/strong\u003e\u003c\/span\u003e - If fast acting is important to you, then we recommend our sublingual powder, tablets, or nasal spray as they bypass digestion. They can provide rapid absorption and reach systemic circulation for a noticable effect in minutes. So whether it's before a quick workout or you need to quickly focus on mental tasks, these products can give you a quick boost when you need it most.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eLong Lasting\u003c\/strong\u003e\u003c\/span\u003e - LIPO NMN lasts longer in the body than our other NMN products. Liposomes protect the active ingredients from digestion and release slowly in the bloodstream up to 24 hours.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eFastest Cognitive Effect\u003c\/strong\u003e\u003c\/span\u003e- The sublingual powder has a very fast effect on physical energy, but the intranasal spray has a much stronger impact on improved cognition (the relief of \"brain fog\").\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eImproved Energy\u003c\/strong\u003e\u003c\/span\u003e- Sublingual delivery is much faster acting and the energy boost is more quickly noticed, but the most common report from users of all NAD+ boosters is increased energy.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eEasiest to Take\u003c\/strong\u003e \u003c\/span\u003e - Some people have trouble swallowing pills or applying powder under the tongue. For those people, LSG NMN is easier because it comes in an easy to apply liquid gel.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eBest Bioavailability\u003c\/strong\u003e \u003c\/span\u003e - Approximately 30% of NMN taken sublingually gets absorbed directly into the bloodstream, while the rest passes through the GI tract and gets broken down into less effective nicotinamide. However liposomal delivery avoids degradation in the GI tract entirely, meaning far more NMN is delivered to the tissues intact.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eBest Cost per Milligram\u003c\/strong\u003e \u003c\/span\u003e - The NMN product with the best price is our sublingual powder as there is very little added cost for processing. Tablets are next. Manufacturing of Liposomes takes the most time and expensive machinery, so cost the most per Milligram.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003e\u003cstrong\u003eBest Overall Value\u003c\/strong\u003e \u003c\/span\u003e - The best overall value is the product which is best in price combined with best bioavailability. Bioavailability is how much of the product actually makes it to the cells intact. For example, our LIPO capsules cost more per milligram to manufacture, but are 3 to 5 times more bioavailable than sublingual products, so are much more cost effective.\u003c\/p\u003e\n\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: fda disclaimer\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=102875\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=253181\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=102875\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"row align-center\"\u003e\n\u003cdiv class=\"col medium-11 small-12 large-11\"\u003e\n\u003cdiv class=\"col-inner text-center\"\u003e\n\u003cdiv class=\"best_price\" style=\"padding: 10px 0 10px 0;\"\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThese statements have not been evaluated by the Food and Drug Administration. \u003c\/span\u003e\u003c\/center\u003e\n\u003ccenter\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/span\u003e\u003c\/center\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-45030940 \u003e .col-inner {\n  padding: 0px 50px 0px 50px;\n  margin: 0px 0px 0px 0px;\n}\n\u003c\/style\u003e\n\u003cdiv class=\"row align-center\" id=\"row-2088276919\"\u003e\n\u003cdiv id=\"col-45030940\" class=\"col medium-11 small-12 large-11\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491521061122,"sku":"850055685154","price":54.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nmns-fast-dissolve-tabs_front_v1.png?v=1774942097"},{"product_id":"slc-enteric-nmn-nicotinamide-mononucleotide-delayed-release-250mg-200ct","title":"NMN SLC Enteric Capsules 200","description":"\u003cp\u003eNAD+ levels in the bloodstream are determined by a delicate balance between production and consumption. SLC NMN helps boost NAD+ production by providing NMN, a direct precursor to NAD+.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote\u003e\u003cp\u003e\"Together, this highlights that a multi-target strategy for NAD+ restoration such as the use of a precursor in combination with inhibitors and\/or activators acting at other key points in the NAD+ network may be the optimum approach to NAD+ restoration.\" (\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006295222000405https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006295222000405\"\u003e1\u003c\/a\u003e)\u003c\/p\u003e\u003c\/blockquote\u003e\n\u003cp\u003eNicotinamide mononucleotide (NMN) is a naturally occurring molecule found in all cells. It is a precursor for NAD+, which is an important molecule for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnergy production\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eDNA repair\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eRegulation of genes\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eCellular health and vitality\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eImmune function\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eRegulation of the sleep-wake cycle\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNAD+ levels naturally decline with age, which research suggests is linked to the onset and progression of age-related diseases.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e This makes increasing NAD+ levels a promising therapeutic target.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eNMN serves as a direct precursor to NAD+, acting as a potent booster to elevate your NAD+ levels.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSLC NMN is designed for enhanced absorption by promoting its interaction with the NMN transporter, Slc12a8.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eThe NMN Transporter – Slc12a8\u003c\/h3\u003e\n\u003cp\u003eA 2019 \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6530925\/\"\u003estudy\u003c\/a\u003e found some NMN can be transported directly through the cell membrane by the Slc12a8 Transporter and converted to NAD+ inside the small intestine.\u003c\/p\u003e\n\u003cp\u003eThe results from their study showed that older mice had increased levels of the transporter, leading to greater increases in NAD+ levels after NMN supplementation compared to young mice.\u003c\/p\u003e\n\u003cblockquote\u003e\u003cp\u003e“​​Therefore, increasing NMN availability or stimulating the function of the NMN transporter could effectively counteract age-associated NAD+ decline in the aged small intestine.”\u003c\/p\u003e\u003c\/blockquote\u003e\n\u003ch3\u003eProtecting NMN from Digestion by Bacteria is Key\u003c\/h3\u003e\n\u003cp\u003eHowever, another \u003ca href=\"https:\/\/assets.researchsquare.com\/files\/rs-87047\/v1_stamped.pdf\"\u003estudy\u003c\/a\u003e showed that most NMN is degraded by bacteria in your gut, limiting the amount of NAD+ that can be produced from standard NMN formulations.\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"alignleft wp-image-243810\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/bacteria-nmn.png\" alt=\"\" width=\"287\" height=\"204\"\u003eThese figures show the effect of gut bacteria on the intestinal levels of NMN (on the left) and NAD+ (on the right) after NMN supplementation.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGray bar:\u003c\/strong\u003e Normal, untreated mice\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eYellow bar:\u003c\/strong\u003e Mice receiving antibiotics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlue bar:\u003c\/strong\u003e Mice receiving NMN\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRed bar:\u003c\/strong\u003e Mice receiving antibiotics and NMN\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe yellow and red bars represent mice given antibiotics to deplete their gut bacteria. Their levels are many times higher than mice with normal gut bacteria.\u003c\/p\u003e\n\u003ch3\u003eSLC NMN\u003c\/h3\u003e\n\u003cp\u003eSLC NMN uses a specially designed capsule that safeguards NMN from degradation by gut bacteria, ensuring that it arrives intact at the Slc12a8 transporter in your gut.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis unique NMN formulation features a number of key advantages to enhances absorption through Slc12a8 and promote your overall well-being:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcid-resistant capsules:\u003c\/strong\u003e SLC NMN capsules are designed to protect the NMN through the stomach, providing more intact NMN in the small intestine for uptake by SLC12a8\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrimethylglycine (TMG):\u003c\/strong\u003e TMG is a natural compound important for methylation, a vital cellular process that is essential for healthy aging and longevity\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune support:\u003c\/strong\u003e SLC NMN includes zinc, which is an important nutrient for immune function\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Bicarbonate: \u003c\/strong\u003eSodium ions are needed for Slc12a8 to work properly, so we include them in our capsules along with NMN. This helps to ensure that more NMN is absorbed into your cells\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: Enteric AR Capsules\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=1617491\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=411924\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=1617491\"\u003e\u003c\/div\u003e\n\u003csection class=\"section\" id=\"section_277739452\"\u003e\n\u003cdiv class=\"bg section-bg fill bg-fill  bg-loaded\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"section-content relative\"\u003e\n\u003cdiv class=\"row\" id=\"row-144727066\"\u003e\n\u003cdiv id=\"col-1910373803\" class=\"col small-12 large-12\"\u003e\n\u003cdiv class=\"col-inner text-left\"\u003e\n\u003cdiv class=\"row\" id=\"row-1372061875\"\u003e\n\u003cdiv id=\"col-1485295077\" class=\"col small-12 large-12\"\u003e\n\u003cdiv class=\"col-inner text-left\" style=\"background-color:rgb(250, 250, 250);\"\u003e\n\u003cdiv id=\"text-1414606498\" class=\"text\"\u003e\n\u003ch3\u003e\u003cspan style=\"font-size: 110%;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #282828;\"\u003eEnteric (Acid-Resistant) Capsules\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003chr\u003e\n\u003cstyle\u003e\n#text-1414606498 {\n  line-height: 1.15;\n  text-align: center;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"tabbed-content\"\u003e\n\u003cul class=\"nav nav-line nav-vertical nav-uppercase nav-size-small nav-left active-on-hover\"\u003e\n\u003cli class=\"tab active has-icon\"\u003e\u003ca href=\"#tab_how-it-works\"\u003e\u003cspan\u003eHOW IT WORKS\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli class=\"tab has-icon\"\u003e\u003ca href=\"#tab_safeguarding-from-digestion\"\u003e\u003cspan\u003eSAFEGUARDING FROM DIGESTION\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli class=\"tab has-icon\"\u003e\u003ca href=\"#tab_enteric-caps-vs-liposomal\"\u003e\u003cspan\u003eEnteric CAPS VS LIPOSOMAL\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"tab-panels\"\u003e\n\u003cdiv class=\"panel active entry-content\" id=\"tab_how-it-works\"\u003e\n\u003cdiv id=\"text-2618334361\" class=\"text\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #282828; font-size: 100%;\"\u003eHow It Works\u003c\/span\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThe enteric coated (acid-resistant) capsules are specifically designed to protect ingredients from the harsh acidic stomach, while safeguarding them from being degraded and digested by bacteria and enzymes.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThe aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract - with NAD+ precursors being particularly vulnerable to this.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThe enteric (acid-resistant) capsules safeguard the ingredients to support better absorption, and a slower \u003cspan class=\"il\"\u003erelease\u003c\/span\u003e into the bloodstream.\u003c\/span\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n#text-2618334361 {\n  text-align: left;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"panel entry-content\" id=\"tab_safeguarding-from-digestion\"\u003e\n\u003cdiv class=\"row\" id=\"row-1781979233\"\u003e\n\u003cdiv id=\"col-305165533\" class=\"col small-12 large-12\"\u003e\n\u003cdiv class=\"col-inner\"\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003e\u003ca href=\"https:\/\/longevityclips.com\/bacteria-in-gastro-intestional-tract-metabolize-nmn-and-impact-nad-metabolome-2\/\" target=\"_blank\" rel=\"noopener\"\u003eResearch\u003c\/a\u003e shows that NAD+ precursors are largely degraded and digested by enzymes and bacteria in the stomach, to other metabolites that are less effective. (\u003ca href=\"https:\/\/longevityclips.com\/bacteria-in-gastro-intestional-tract-metabolize-nmn-and-impact-nad-metabolome-2\/\" target=\"_blank\" rel=\"noopener\"\u003e1\u003c\/a\u003e) \u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 100%; color: #282828;\"\u003eNMN Degraded By Bacteria in the Stomach\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-19-at-13-01-58-Bioavailability-Issues-_E2_80_93-RENUE-BY-SCIENCE.png\"\u003e\u003cimg class=\"alignleft wp-image-1617995\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-19-at-13-01-58-Bioavailability-Issues-_E2_80_93-RENUE-BY-SCIENCE.png\" alt=\"\" width=\"210\" height=\"188\"\u003e\u003c\/a\u003eThis chart shows a significant elevation in NMN levels after antibiotic administration. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis can be attributed to the antiobiotic's impact on stomach bacteria, which causes a reduction in overall diversity. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #282828; font-size: 100%;\"\u003e\u003cstrong\u003eNR Degraded By Bacteria in the Stomach\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7194078\/\"\u003estudy\u003c\/a\u003e reveals a substantial breakdown of NR into various metabolites (NAM, NA, NAR) within the colon. The blue bars represent orally administered NR.\u003c\/span\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-18-at-10_40_50_E2_80_AFAM.png\"\u003e\u003cimg class=\"wp-image-1617554 alignright\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-18-at-10_40_50_E2_80_AFAM.png\" alt=\"\" width=\"340\" height=\"172\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eIn mice without gut bacteria (GF NR), almost none of the NR is converted into the metabolites mentioned.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis suggests that gut bacteria plays a significant role in the breakdown of NR in the digestive system.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"panel entry-content\" id=\"tab_enteric-caps-vs-liposomal\"\u003e\n\u003cdiv id=\"text-2757676375\" class=\"text\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #282828; font-size: 100%;\"\u003e\u003cstrong\u003eDelivery Systems to Improve Absorption\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eSeveral delivery systems have been developed to protect NAD+ and precursors from being broken down and to enhance their absorption.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eIn other products, we use advanced Liposomal technology which protect NAD+, NMN, and NR from degradation in the GI tract and liver, but this delivery system adds significant cost.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eWe are committed to providing diverse and effective delivery methods that cater to various budgets and preferences. We believe that enteric (acid-resistant) capsules are superior to the standard capsules sold online, offering improved absorption at a lower cost than our competitors.\u003c\/span\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n#text-2757676375 {\n  text-align: left;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-1485295077 \u003e .col-inner {\n  padding: 15px 0px 0px 15px;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#row-1372061875 \u003e .col \u003e .col-inner {\n  background-color: rgb(255,255,255);\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-1910373803 \u003e .col-inner {\n  padding: 12px 0px 0px 0px;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#section_277739452 {\n  padding-top: 10px;\n  padding-bottom: 10px;\n}\n#section_277739452 .ux-shape-divider--top svg {\n  height: 150px;\n  --divider-top-width: 100%;\n}\n#section_277739452 .ux-shape-divider--bottom svg {\n  height: 150px;\n  --divider-width: 100%;\n}\n\u003c\/style\u003e\n\u003c\/section\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45491521093890,"sku":"850055685055","price":58.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nmn-slc-enteric-capsules-200_front_v1.png?v=1774942080"},{"product_id":"slc-enteric-nmn-zinc-free-nicotinamide-mononucleotide-delayed-release-250mg","title":"NMN SLC Enteric Capsules 60","description":"\u003cp\u003eNAD+ levels in the bloodstream are determined by a delicate balance between production and consumption. SLC NMN helps boost NAD+ production by providing NMN, a direct precursor to NAD+.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote\u003e\u003cp\u003e\"Together, this highlights that a multi-target strategy for NAD+ restoration such as the use of a precursor in combination with inhibitors and\/or activators acting at other key points in the NAD+ network may be the optimum approach to NAD+ restoration.\" (\u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006295222000405https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006295222000405\"\u003e1\u003c\/a\u003e)\u003c\/p\u003e\u003c\/blockquote\u003e\n\u003cp\u003eNicotinamide mononucleotide (NMN) is a naturally occurring molecule found in all cells. It is a precursor for NAD+, which is an important molecule for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnergy production\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eDNA repair\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eRegulation of genes\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eCellular health and vitality\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eImmune function\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eRegulation of the sleep-wake cycle\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNAD+ levels naturally decline with age, which research suggests is linked to the onset and progression of age-related diseases.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e This makes increasing NAD+ levels a promising therapeutic target.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eNMN serves as a direct precursor to NAD+, acting as a potent booster to elevate your NAD+ levels.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eSLC NMN is designed for enhanced absorption by promoting its interaction with the NMN transporter, Slc12a8.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eThe NMN Transporter – Slc12a8\u003c\/h3\u003e\n\u003cp\u003eA 2019 \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6530925\/\"\u003estudy\u003c\/a\u003e found some NMN can be transported directly through the cell membrane by the Slc12a8 Transporter and converted to NAD+ inside the small intestine.\u003c\/p\u003e\n\u003cp\u003eThe results from their study showed that older mice had increased levels of the transporter, leading to greater increases in NAD+ levels after NMN supplementation compared to young mice.\u003c\/p\u003e\n\u003cblockquote\u003e\u003cp\u003e“​​Therefore, increasing NMN availability or stimulating the function of the NMN transporter could effectively counteract age-associated NAD+ decline in the aged small intestine.”\u003c\/p\u003e\u003c\/blockquote\u003e\n\u003ch3\u003eProtecting NMN from Digestion by Bacteria is Key\u003c\/h3\u003e\n\u003cp\u003eHowever, another \u003ca href=\"https:\/\/assets.researchsquare.com\/files\/rs-87047\/v1_stamped.pdf\"\u003estudy\u003c\/a\u003e showed that most NMN is degraded by bacteria in your gut, limiting the amount of NAD+ that can be produced from standard NMN formulations.\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"alignleft wp-image-243810\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/bacteria-nmn.png\" alt=\"\" width=\"287\" height=\"204\"\u003eThese figures show the effect of gut bacteria on the intestinal levels of NMN (on the left) and NAD+ (on the right) after NMN supplementation.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGray bar:\u003c\/strong\u003e Normal, untreated mice\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eYellow bar:\u003c\/strong\u003e Mice receiving antibiotics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlue bar:\u003c\/strong\u003e Mice receiving NMN\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRed bar:\u003c\/strong\u003e Mice receiving antibiotics and NMN\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe yellow and red bars represent mice given antibiotics to deplete their gut bacteria. Their levels are many times higher than mice with normal gut bacteria.\u003c\/p\u003e\n\u003ch3\u003eSLC NMN\u003c\/h3\u003e\n\u003cp\u003eSLC NMN uses a specially designed capsule that safeguards NMN from degradation by gut bacteria, ensuring that it arrives intact at the Slc12a8 transporter in your gut.\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis unique NMN formulation features a number of key advantages to enhances absorption through Slc12a8 and promote your overall well-being:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcid-resistant capsules:\u003c\/strong\u003e SLC NMN capsules are designed to protect the NMN through the stomach, providing more intact NMN in the small intestine for uptake by SLC12a8\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrimethylglycine (TMG):\u003c\/strong\u003e TMG is a natural compound important for methylation, a vital cellular process that is essential for healthy aging and longevity\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune support:\u003c\/strong\u003e SLC NMN includes zinc, which is an important nutrient for immune function\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Bicarbonate: \u003c\/strong\u003eSodium ions are needed for Slc12a8 to work properly, so we include them in our capsules along with NMN. This helps to ensure that more NMN is absorbed into your cells\u003cspan style=\"font-weight: 400;\"\u003e†\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"block-edit-link\" data-title=\"Edit Block: Enteric AR Capsules\" data-backend=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=1617491\u0026amp;action=edit\" data-link=\"https:\/\/renuebyscience.com\/june\/wp-admin\/post.php?post=411924\u0026amp;action=edit\u0026amp;app=uxbuilder\u0026amp;type=editor\u0026amp;edit_post_id=1617491\"\u003e\u003c\/div\u003e\n\u003csection class=\"section\" id=\"section_277739452\"\u003e\n\u003cdiv class=\"bg section-bg fill bg-fill  bg-loaded\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"section-content relative\"\u003e\n\u003cdiv class=\"row\" id=\"row-144727066\"\u003e\n\u003cdiv id=\"col-1910373803\" class=\"col small-12 large-12\"\u003e\n\u003cdiv class=\"col-inner text-left\"\u003e\n\u003cdiv class=\"row\" id=\"row-1372061875\"\u003e\n\u003cdiv id=\"col-1485295077\" class=\"col small-12 large-12\"\u003e\n\u003cdiv class=\"col-inner text-left\" style=\"background-color:rgb(250, 250, 250);\"\u003e\n\u003cdiv id=\"text-1414606498\" class=\"text\"\u003e\n\u003ch3\u003e\u003cspan style=\"font-size: 110%;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #282828;\"\u003eEnteric (Acid-Resistant) Capsules\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003chr\u003e\n\u003cstyle\u003e\n#text-1414606498 {\n  line-height: 1.15;\n  text-align: center;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"tabbed-content\"\u003e\n\u003cul class=\"nav nav-line nav-vertical nav-uppercase nav-size-small nav-left active-on-hover\"\u003e\n\u003cli class=\"tab active has-icon\"\u003e\u003ca href=\"#tab_how-it-works\"\u003e\u003cspan\u003eHOW IT WORKS\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli class=\"tab has-icon\"\u003e\u003ca href=\"#tab_safeguarding-from-digestion\"\u003e\u003cspan\u003eSAFEGUARDING FROM DIGESTION\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli class=\"tab has-icon\"\u003e\u003ca href=\"#tab_enteric-caps-vs-liposomal\"\u003e\u003cspan\u003eEnteric CAPS VS LIPOSOMAL\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"tab-panels\"\u003e\n\u003cdiv class=\"panel active entry-content\" id=\"tab_how-it-works\"\u003e\n\u003cdiv id=\"text-2618334361\" class=\"text\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #282828; font-size: 100%;\"\u003eHow It Works\u003c\/span\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThe enteric coated (acid-resistant) capsules are specifically designed to protect ingredients from the harsh acidic stomach, while safeguarding them from being degraded and digested by bacteria and enzymes.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThe aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract - with NAD+ precursors being particularly vulnerable to this.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThe enteric (acid-resistant) capsules safeguard the ingredients to support better absorption, and a slower \u003cspan class=\"il\"\u003erelease\u003c\/span\u003e into the bloodstream.\u003c\/span\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n#text-2618334361 {\n  text-align: left;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"panel entry-content\" id=\"tab_safeguarding-from-digestion\"\u003e\n\u003cdiv class=\"row\" id=\"row-1781979233\"\u003e\n\u003cdiv id=\"col-305165533\" class=\"col small-12 large-12\"\u003e\n\u003cdiv class=\"col-inner\"\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003e\u003ca href=\"https:\/\/longevityclips.com\/bacteria-in-gastro-intestional-tract-metabolize-nmn-and-impact-nad-metabolome-2\/\" target=\"_blank\" rel=\"noopener\"\u003eResearch\u003c\/a\u003e shows that NAD+ precursors are largely degraded and digested by enzymes and bacteria in the stomach, to other metabolites that are less effective. (\u003ca href=\"https:\/\/longevityclips.com\/bacteria-in-gastro-intestional-tract-metabolize-nmn-and-impact-nad-metabolome-2\/\" target=\"_blank\" rel=\"noopener\"\u003e1\u003c\/a\u003e) \u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 100%; color: #282828;\"\u003eNMN Degraded By Bacteria in the Stomach\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-19-at-13-01-58-Bioavailability-Issues-_E2_80_93-RENUE-BY-SCIENCE.png\"\u003e\u003cimg class=\"alignleft wp-image-1617995\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-19-at-13-01-58-Bioavailability-Issues-_E2_80_93-RENUE-BY-SCIENCE.png\" alt=\"\" width=\"210\" height=\"188\"\u003e\u003c\/a\u003eThis chart shows a significant elevation in NMN levels after antibiotic administration. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis can be attributed to the antiobiotic's impact on stomach bacteria, which causes a reduction in overall diversity. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #282828; font-size: 100%;\"\u003e\u003cstrong\u003eNR Degraded By Bacteria in the Stomach\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7194078\/\"\u003estudy\u003c\/a\u003e reveals a substantial breakdown of NR into various metabolites (NAM, NA, NAR) within the colon. The blue bars represent orally administered NR.\u003c\/span\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-18-at-10_40_50_E2_80_AFAM.png\"\u003e\u003cimg class=\"wp-image-1617554 alignright\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0636\/4803\/9091\/files\/Screenshot-2024-01-18-at-10_40_50_E2_80_AFAM.png\" alt=\"\" width=\"340\" height=\"172\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eIn mice without gut bacteria (GF NR), almost none of the NR is converted into the metabolites mentioned.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eThis suggests that gut bacteria plays a significant role in the breakdown of NR in the digestive system.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"panel entry-content\" id=\"tab_enteric-caps-vs-liposomal\"\u003e\n\u003cdiv id=\"text-2757676375\" class=\"text\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #282828; font-size: 100%;\"\u003e\u003cstrong\u003eDelivery Systems to Improve Absorption\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eSeveral delivery systems have been developed to protect NAD+ and precursors from being broken down and to enhance their absorption.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eIn other products, we use advanced Liposomal technology which protect NAD+, NMN, and NR from degradation in the GI tract and liver, but this delivery system adds significant cost.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 90%;\"\u003eWe are committed to providing diverse and effective delivery methods that cater to various budgets and preferences. We believe that enteric (acid-resistant) capsules are superior to the standard capsules sold online, offering improved absorption at a lower cost than our competitors.\u003c\/span\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n#text-2757676375 {\n  text-align: left;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-1485295077 \u003e .col-inner {\n  padding: 15px 0px 0px 15px;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#row-1372061875 \u003e .col \u003e .col-inner {\n  background-color: rgb(255,255,255);\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#col-1910373803 \u003e .col-inner {\n  padding: 12px 0px 0px 0px;\n}\n\u003c\/style\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n#section_277739452 {\n  padding-top: 10px;\n  padding-bottom: 10px;\n}\n#section_277739452 .ux-shape-divider--top svg {\n  height: 150px;\n  --divider-top-width: 100%;\n}\n#section_277739452 .ux-shape-divider--bottom svg {\n  height: 150px;\n  --divider-width: 100%;\n}\n\u003c\/style\u003e\n\u003c\/section\u003e","brand":"Renue By Science","offers":[{"title":"Default Title","offer_id":45501453566210,"sku":"850055685208","price":27.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/5785\/0114\/files\/nmn-slc-enteric-capsules-60_front_v1.png?v=1774942090"}],"url":"https:\/\/renuebyscience.com\/collections\/nmn-only.oembed","provider":"Renue By Science","version":"1.0","type":"link"}