Search found 65 matches
- Sun Nov 17, 2019 5:56 pm
- Forum: NMN
- Topic: The first NMN study in humans is published
- Replies: 17
- Views: 20678
Re: The first NMN study in humans is published
The single oral administration of NMN capsules in the doses 100, 250 and 500 mg in 10 healthy Japanese men was shown to be safe. oh, your cut and past missed the first and important sentence.... Recent studies have revealed that decline in cellular nicotinamide adenine dinucleotide (NAD+) levels ca...
- Sun Nov 17, 2019 5:49 pm
- Forum: NMN
- Topic: The first NMN study in humans is published
- Replies: 17
- Views: 20678
Re: The first NMN study in humans is published
The single oral administration of NMN capsules in the doses 100, 250 and 500 mg in 10 healthy Japanese men was shown to be safe. "Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men" The administrat...
- Sun Nov 17, 2019 5:28 pm
- Forum: NAD+
- Topic: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
- Replies: 7
- Views: 14043
Re: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
Did you check out the article he posted? The link is there and it explains how NMN turns into NAD in the cell. Thanks Fred (sort of), my question is simply - what is the difference between taking NMN (and having it metabolised into NAD+) and taking it as NAD+, if any. There are no human trials of o...
- Sun Nov 17, 2019 3:01 pm
- Forum: NAD+
- Topic: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
- Replies: 7
- Views: 14043
Re: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
It is an exciting time for NAD+ especially in the field of aging. I agree that NAD+ holds some of the factors that can slow the aging process. In fact in Alzheimer’s disease it has been shown through animal models that DNA damage can be repaired, improved cognition and motor function can be achieve...
- Sat Nov 16, 2019 5:11 pm
- Forum: NAD+
- Topic: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
- Replies: 7
- Views: 14043
Re: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
It is an exciting time for NAD+ especially in the field of aging. I agree that NAD+ holds some of the factors that can slow the aging process. In fact in Alzheimer’s disease it has been shown through animal models that DNA damage can be repaired, improved cognition and motor function can be achieve...
- Thu Nov 14, 2019 9:50 pm
- Forum: NMN
- Topic: The magic 500mg threshold :)
- Replies: 72
- Views: 109525
Re: The magic 500mg threshold :)
I agree wholeheartedly. NAD+ seems to enhance my sleep where NMN with me, has a stimulating effect. :shock: I am not following sorry. Isn't NAD+ just one step further down the metabolism pathway than NMN? FYI - my finger and toe nails didn't harden until I started taking NAD+(know I can see a disti...
- Thu Nov 14, 2019 9:47 pm
- Forum: NMN
- Topic: The magic 500mg threshold :)
- Replies: 72
- Views: 109525
Re: The magic 500mg threshold :)
This topic is most enlightening. Firstly, the brain is a powerful tool and like Newage, I just haven't seemed to age mentally since hitting 50 and my body has responded in kind. Second, as with all supplements I take, I space them throughout the day so my body can process just that dosage. With res...
- Thu Nov 14, 2019 9:43 pm
- Forum: NAD+
- Topic: NAD+ Nasal Spray Dosage
- Replies: 28
- Views: 45443
Re: NAD+ Nasal Spray Dosage
Hey guys has anyone here tried the new product Cenergy yet? I just got a bottle and been on it now for 2 days. So far so good other than alittle discomfort if you do more than 2 sprays per nostril. I will keep you posted on results noted. I have just finished my first bottle, very happy with the re...
- Wed Nov 13, 2019 8:07 pm
- Forum: NMN
- Topic: The NMN transporter is found: how NMN gets into cells
- Replies: 6
- Views: 9100
Re: The NMN transporter is found: how NMN gets into cells
I haven´t seen this posted before so adding it for those who haven´t read it. The elusive NMN transporter is found Lindsay E. Wu & David A. Sinclair Nature Metabolism volume 1, pages8–9(2019) Strategies to restore levels of the enzyme cofactor nicotinamide adenine dinclueotide (NAD) late in lif...
- Wed Nov 13, 2019 8:05 pm
- Forum: NMN
- Topic: Post your weight and dosage thread
- Replies: 32
- Views: 39133
Re: Post your weight and dosage thread
It's already been posted in the forum, but i'm referencing it here - worth a watch if you haven't already: https://www.youtube.com/watch?v=5DtWqzalEnc&feature=youtu.be& From the comments, referencing a study done "Older mice that were given NMN (300 mg/kg/day) experienced delayed aging...