NAD+ Forums

It seems almost all of the newer RBS products are being formulated only as liposomal versions. I know that liposomal formulations are able to bypass the gut and enter the bloodstream more easily, but is this necessarily a desirable thing for all of these supplements? We're taking these in the first ...

Been asking myself that as I consider trying weekly rapamycin dosing. With generics, 30mg can be had for about $150. 3mg dose once weekly makes that 10 weeks supply, or about $67/month. Added on to my NMN and pterostilbene that would take me close to $125 a month. Not terrible when you consider the ...

Apparently ABS is switching back to the old, less acidic formula around the new year.

Dr Sinclair has said a few times that while he thinks NMN helps prevent cancer, he would be cautious with anyone who had an active cancer and defer 100% to the oncologists who can devise an overall treatment plan for that cancer.

https://twitter.com/Blagosklonny/status/1441539123349790720?s=20 Rapamycin high dose intermittently Low-Carb or Low Carb/Cal diets, time-restricted, IF Physical exercise daily Sun, Sunbath/Vit D3 Metformin low/medium dose Angiotensin II inhibitors Aspirin low dose Lithium low dose DHEA, L-Ornithine ...

I would find a doctor who offers nad+ treatments. Anything injected must be sterile and at an even higher purity than orally consumed compounds. Also it is unclear if NMN doesn’t actually need to go through the digestive tract to work. There is some evidence that NMN actually increases NAD+ through ...

Yes we are living in exciting times as we will witness more scientific break throughs in aging and how to reverse it.    Yes, and the longevity race is still continuing even though we are presently all experiencing one of the worst worldwide pandemics to affect mankind.. If anything it still shows ...

Yamanaka factors are being studied by Dr David Sinclair’s lab ( they regenerated an entire optic nerve which before has been completely impossible) and also a handful of other labs like Calico, the Google biotech offshoot. It is really great to see so multiple labs see promise in the same technology...

From what I understand rapamycin has different effects at different doses. When used once a week, it only inhibits mTOR1 ( that's what we want to inhibit). When used daily, it inhbits mTOR2 (that's the one we don't want to inhibit)

This is the premise of how they could potentially be a net harmful thing. I have no idea personally, I just had never considered that there may be less than positive long term effects: Here is the argument: 1) theoretically, senolytics should make things worse and 2) the available data support this ...