Search found 4 matches

by drpatrick
Tue Dec 03, 2019 1:06 am
Forum: Healthy Aging News and Research
Topic: Is aging really a disease?
Replies: 12
Views: 26289

Re: Is aging really a disease?

a particular quality, habit, or disposition regarded as adversely affecting a person or group of people. Middle English (in the sense ‘lack of ease; inconvenience’): from Old French desaise ‘lack of ease’, from des- (expressing reversal) + aise ‘ease’. We consider diabetes, cancer, dementia, heart ...
by drpatrick
Thu Nov 21, 2019 1:03 am
Forum: Healthy Aging News and Research
Topic: Can Boosting NAD+ Cause Negative Effects for Certain Gene Mutations?
Replies: 8
Views: 16511

Re: Can Boosting NAD+ Cause Negative Effects for Certain Gene Mutations?

Hi James, here are a few key sentences from the interesting article mentioned by Drdavid: Increased NAD levels enhance glycolysis and fuel cancer cells. In fact, nicotinamide phosphoribosyltransferase (Nampt), a rate-limiting enzyme for NAD synthesis in mammalian cells, is frequently amplified in se...
by drpatrick
Wed Nov 20, 2019 2:57 pm
Forum: NMN
Topic: Baseline NMN/NAD+ level?
Replies: 14
Views: 21436

Re: Baseline NMN/NAD+ level?

hsCRP is a marker of inflammation and higher levels are associated with increased risk of heart disease. hsCRP can increase in any state of inflammation, including recent illness, so could reasonably get a few levels and take the lowest one as your baseline. Telomere length is not available in Canad...
by drpatrick
Wed Nov 20, 2019 2:48 pm
Forum: Miscellaneous Topics
Topic: Timing Blood Pressure Meds for maximum benefits
Replies: 2
Views: 9875

Re: Timing Blood Pressure Meds for maximum benefits

In my work as a hospitalist, I often switch patients' anti-hypertensive medication from morning to bedtime for improved control. It doesn't always work, but often helps.