NAD+ Forums

I think it would be overkill if you are under the age of 60   Thanks. I'm 43. I know some people like to do one or the other, in terms of raising NAD+, either inhibiting CD 38 or taking a precursor like NMN.  Apigenin is known to have a host of health benefits as Boxcost said. I'd wonder if just ta...

I finally got my hands on some lipo NMN and lipo Apigenin. If the lipo NMN is 3 to 5 times stronger (?), or so I've heard, than one 250 capsule should suffice for the day for most standards right (ending up to about a gram)? but lipo apigenin could also raise NAD+ levels by itself by inhibiting cd 3...

But the feeling good for a week or two, then back to original energy has been there each increment for me as well.   Welcome to the wonderful world of biohacking!  It can be frustrating but in regards to whether homeostasis is sort of "throwing away" the gains in NAD+ through supplementat...

Definitely. I've been taking NMN for three months. 250, felt good for a week or two, then back to where I started. 500, good for a week or two, back to where I started in terms of energy. 750, same.  I've felt a noticeable increase in libido, and I'm looking better, so the NMN is accomplishing some ...

Thumbs up for the caffeine tip. I was drinking caffeinated sodas. Since stopping its helped I'm also back up to 750 mg. I feel this is the right dose at this point. I believe its near the dose the mice used in the aforementioned YouTube video at my weight. Instead of thinking of NMN as a Red Bull dr...

Went back to 250 and feel better than when I was on 500mg I'm not an authority at all, but I saw a mouse study presented by a guy on YouTube, I believe, that said mice actually had more energy on 100mg/kg/day than 300mg/kg/day study  - Starts around the 3 minute mark I don't know what dosages that w...

Went up to 750 last night and also had a higher disturbance than on nights I take 500. Does it take the body time to acclimate to certain dosages?  Also, I felt better, less lethargic, on 250. Does taking too much have the reverse affect?   It is very rare to have feedback like yours and I believe ...

Went up to 750 last night and also had a higher disturbance than on nights I take 500.

Does it take the body time to acclimate to certain dosages? 

Also, I felt better, less lethargic, on 250. Does taking too much have the reverse affect?

I think I've gotten part of the answer. For two days I randomly stopped taking my daily 500mg dosage and had even worse sleep than the other days. When I started taking the 250 I had no sleep disturbance, and I think the sleep issues started a week after I went to 500 I'm going to assume the sleep d...

I'm 43, work out, and take a large stack of vitamins/herbs/other supplements, so several things can be at play. I also have a possible medical condition that could be causing lethargy  I just started last month on 250 mg on NMN, now on 500mg of the sublingual tablets. I want to say around the time I...