The 4 supplements used in the trial were:
- L-Serine, 12 grams
- Nicotinamide Riboside, 1 gram
- N-acetyl-L-cysteine (NAC), 2.5 grams
- L-carnitine, 3.5 grams
The new approach uses what are known as "combined metabolic activators". This combination could be helpful in a new theory of Alzheimer's disease, namely that Alzheimer's is closely linked to metabolic disorders, mitochondrial dysfunction, and oxidative stress, all of which can lead to neurodegeneration.
The new treatment can target multiple pathways at the same time. Previous research has identified reduced glutathione levels in Alzheimer's patients and glutathione is a powerful antioxidant.
Nicotinamide Riboside or NMN increase NAD+ levels and NAD+ is central to our metabolism. Finally, L-carnitine helps with fatty acid metabolism. Combining these 4 supplements supports our metabolism at multiple different levels.
For more, watch Dr. Brad Stanfield's new video on this topic: