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Thanks. I'm 43. I know some people like to do one or the other, in terms of raising NAD+, either inhibiting CD 38 or taking a precursor like NMN.
Boxcost wrote: ↑Thu Mar 24, 2022 3:38 pm I am 54 and taking both.
Apigenin is not just about NAD+. It is also anti-cancer, lowers cortisol, lowers inflammation (bad at any age) and increases testosterone as per recent study: https://pubmed.ncbi.nlm.nih.gov/20537519/
I am also on 2 x NAD+ Complete (600mg) and 1 x LIPO NMN (250mg) and 1 x dose of NMN/reveratrol (240mg) - so just over a gram of NAD+ boosters in LIPO formulation and feel great!
I don't think it's overkill to do both. Try to judge by whether you feel more energy throughout the day. If you can't sleep, back off on dosage. These are inexact methods but you can always take the NAD test.LiveLong wrote: ↑Thu Mar 24, 2022 12:56 pm I finally got my hands on some lipo NMN and lipo Apigenin. If the lipo NMN is 3 to 5 times stronger (?), or so I've heard, than one 250 capsule should suffice for the day for most standards right (ending up to about a gram)? but lipo apigenin could also raise NAD+ levels by itself by inhibiting cd 38?
Is it overkill to take both?
I was on about 500mg NMN SL for the first 11 months, 750mg about 4-5 months and then last 12 months approx a gram. The specific combination / dosage I am currently on is the last month only. That is I replaced a 250mg normal powder in slow release capsules I was taking with the NMN LIPO 250mg and another 250mg SL NMN with a NAD+ Complete LIPO.LiveLong wrote: ↑Thu Mar 24, 2022 6:38 pmBoxcost wrote: ↑Thu Mar 24, 2022 3:38 pm I am 54 and taking both.
Apigenin is not just about NAD+. It is also anti-cancer, lowers cortisol, lowers inflammation (bad at any age) and increases testosterone as per recent study: https://pubmed.ncbi.nlm.nih.gov/20537519/
I am also on 2 x NAD+ Complete (600mg) and 1 x LIPO NMN (250mg) and 1 x dose of NMN/reveratrol (240mg) - so just over a gram of NAD+ boosters in LIPO formulation and feel great!
So lipo apigenin 35mg, while taking over a gram of lipo NAD+ precursor? That seems a lot, but I'll take your word for it on how you feel. Did you work up to that?
There are so many additional benefits to Apigenin that I am looking to take both. Thanks for posting this as i am aware of it now.LiveLong wrote: ↑Thu Mar 24, 2022 12:56 pm I finally got my hands on some lipo NMN and lipo Apigenin. If the lipo NMN is 3 to 5 times stronger (?), or so I've heard, than one 250 capsule should suffice for the day for most standards right (ending up to about a gram)? but lipo apigenin could also raise NAD+ levels by itself by inhibiting cd 38?
Is it overkill to take both?
Boxcost wrote: ↑Thu Mar 24, 2022 3:38 pm Apigenin is not just about NAD+. It is also anti-cancer, lowers cortisol, lowers inflammation (bad at any age) and increases testosterone as per recent study: https://pubmed.ncbi.nlm.nih.gov/20537519/
RobSmith wrote: ↑Sat Mar 26, 2022 2:58 pmBoxcost wrote: ↑Thu Mar 24, 2022 3:38 pm Apigenin is not just about NAD+. It is also anti-cancer, lowers cortisol, lowers inflammation (bad at any age) and increases testosterone as per recent study: https://pubmed.ncbi.nlm.nih.gov/20537519/
I think CD38 accelerates as one gets older which is probably what decreases the NAD+. I've cut right back on the NMN of late whilst adding dried parsley (good source of Apigenin) to my green salads and I haven't noticed any difference in my health or physical performance.
I'm under 60 so given the extra benefits of Apigenin, once I've finished my current stock of NMN I'm going to switch to RBS's Apigenin and stop the NMN and see what happens. If I notice a deterioration I'll go back to my current NMN twice a week top up.