Senolytics ⇒ Interesting chart of sensescent cells by age

[rhett]

Came across this chart on twitter showing accumulation of senescent cells by age:

https://twitter.com/Mangan150/status/12 ... 2145010690

The black line is human mortality, the red line is senescent cell accumulation. A few super interesting things:

1. They match almost exactly
2. From data start at 20 years to about 40 years, senescent cell levels seem relatively flat. Then levels begin a a fairly dramatic rise that continues until data end.

This suggests to me a good rationale for starting senolytics (and maybe even weekly rapamycin) around age 40.

[Drdavid]

Thanks for the chart. I had not seen this before but you are correct that there seems to be a parallel. Senolytics may offer an answer

[drkris69]

Yes very cool.

[drkris69]

And for those that don't know what senolytics are here's an article.


https://www.lifespan.io/news/senolytics

[Newage]

And for those that don't know what senolytics are here's an article.


https://www.lifespan.io/news/senolytics

Thanks drkris69
The more information, the better on this interesting subject..

[drkris69]

How you doing newage? Life back to normal??

[NewLifeScience]

Came across this chart on twitter showing accumulation of senescent cells by age:

https://twitter.com/Mangan150/status/12 ... 2145010690

The black line is human mortality, the red line is senescent cell accumulation. A few super interesting things:

1. They match almost exactly
2. From data start at 20 years to about 40 years, senescent cell levels seem relatively flat. Then levels begin a a fairly dramatic rise that continues until data end.

This suggests to me a good rationale for starting senolytics (and maybe even weekly rapamycin) around age 40.

So basically as soon as the average human stops having children.

I have known about extremely large families where the mother had children into her forties and lived into their late 90s

[Newage]

How you doing newage? Life back to normal??

Pretty much drkris69, thank you.
Still a way to go with summer and the fire season though..
“What doesn’t kill you toughens you up”
Can be a harsh country at times..

[drkris69]

Yes sir I agree. Glad to hear that and keep on truckin on!

[OzSport]

Interesting graph, thanks rhett!