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Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Thu Sep 16, 2021 4:25 pm
by Pickleball101
G’day,[left]
Recently, I had the opportunity to sit down with a legend in the health and wellness space, Dr. Rhonda Patrick. Rhonda and I have something in common. We both have spent time at the bench studying aging, in her case with my esteemed colleague Professor Andy Dillin at Berkeley.

Often I receive comments on my social feeds saying how overwhelming the amount of information is out there about health recommendations and longevity research. Because it's so well organized, I think this conversation will help add clarity. In addition to releasing a full ~1:12 hour interview, Rhonda also broke the discussion into clips for those who would prefer to learn in digestible bits. I've put links to all 22 clips below and here's a link to iTunes.

Best wishes,
David  Image Full Interview on Informational Theory of Aging
Dr Rhonda Patrick
Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & MoreFoundMyFitness Clips [left]1. History and discovery of longevity genes [Link]
2. The link between sirtuins, calorie restriction, fasting and the insulin pathway [Link]
3. How NAD+ resets the circadian clock and regulates sirtuins [Link]
4. NAD+ and resveratrol levels affect the aging process [Link]
5. Why we lose NAD+ in aging—DNA repair & inflammation [Link]
6. Link between sirtuin pathway and the Horvath Clock [Link]
7. Discovery of genes that reset the Horvath Clock [Link]
8. Induced stem cells used to heal eye-related diseases [Link]
9. Dr. Sinclair explains reprogramming of epigenetics via the Informational Theory of Aging [Link]
10. NAD+ boosters: NR, NMN, and how they affect sirtuins [Link]
11. Does your body become fitter if your food is stressed out? [Link]
12. Resveratrol improves aortic stiffness (in rhesus monkeys) [Link]
13. Resveratrol's impact on the cardiovascular system [Link]
14. Dosage & supplement factors to consider for resveratrol supplementation [Link]
15. Resveratrol shown to have positivity impact on brand health (or in Alzheimer's Disease prevention [Link]
16. Increased NAD+ levels have positive impacts on vascular dementia [Link]
17. NR vs. NMN: dosing and effects on NAD+ levels [Link]
18. Why keeping NR & NMN supplements cold is crucial [Link]
19. NMN supplementation improved health parameters in mice [Link]
20. Why NR is more commonly used in studies (vs. NMN) [Link]
21. Dr. David Sinclair's personal dosage and supplementation habits [Link]
22. The relationship between sleep and insulin sensitivity [Link]
23. Dr. David Sinclair's personal sleep habits [Link]
24. Resveratrol: dosage considerations and effects on cardiovascular health [Link][/left][/left]
 
 
 
 

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Fri Sep 17, 2021 7:58 pm
by smokinjoe
Wow, this is well researched and thorough. Thank you!

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Mon Sep 20, 2021 3:27 pm
by Pickleball101
Yes, Joe, This ones a keeper. Dr. Sinclair took the time to break down 24 of his discoveries into individual linked research! What a Gift!

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Mon Sep 20, 2021 8:34 pm
by Newage
Pickleball101 wrote: Mon Sep 20, 2021 3:27 pm Yes, Joe, This ones a keeper. Dr. Sinclair took the time to break down 24 of his discoveries into individual linked research! What a Gift!

 
Good job Pickleball 101...👍
 

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Tue Sep 21, 2021 11:28 am
by drkris69
Yes great stuff, watched this and took notes.

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Tue Sep 21, 2021 2:42 pm
by TedB
My 2 favourite biologists, Dr. Sinclair and Dr. Rhonda Patrick

We should [in this in the longevity category.

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Thu Sep 23, 2021 2:08 am
by Newage
TedB wrote: Tue Sep 21, 2021 2:42 pm My 2 favourite biologists, Dr. Sinclair and Dr. Rhonda Patrick

We should [in this in the longevity category.

 
I agree TedB. What they don’t know is not worth knowing..
 

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Fri Sep 24, 2021 8:21 pm
by canadahealthy
Great to watch and rewatch!

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Fri Sep 24, 2021 8:55 pm
by CeeJayBee
Well I learned that if resveratrol is brown it is no good.

Opened my capsules - dark brown powder.

Time to reconsider.

Re: Dr. Sinclair's links to 24 of his Anti-Aging Discoveries

Posted: Fri Sep 24, 2021 9:48 pm
by Boxcost
Try megaresveratrol, good on their disclosure i.e. particle size, colour, etc. For me the benchmark trans-resveratrol (and trans-pterostilbene) capsules:
https://megaresveratrol.net/product/meg ... rian-caps/


The benchmark for lipsomal delivery is obviously: https://alivebyscience.com/product/nmn- ... ublingual/