NAD+ Forums

NewLifeScience wrote: ↑Fri Dec 03, 2021 7:41 am There are a couple of things I have observed and I hope this helps.

First, i take any NMN product well before supper and if i was taking all 750mg at once, would like take it in the morning. Second, with such regular high daily dosing you are going to want to take TMG, which replenishes the methyl groups that are burned up through the process (methylation). 

I think if you try these 2 things you will find your issues go away.

Welcome to the group. Please keep us informed of your experience.

 

RobSmith wrote: ↑Fri Dec 03, 2021 9:38 am Hi,
I found that having a bone broth in the evening gives me a completely undisturbed 7-8 hours sleep. Apparently it is because of the glycine content. 
Maybe you could try this to see if it helps before cutting back on the NMN.
 

 

soniad wrote: ↑Fri Dec 03, 2021 3:18 pm

NewLifeScience wrote: ↑Fri Dec 03, 2021 7:41 am There are a couple of things I have observed and I hope this helps.

First, i take any NMN product well before supper and if i was taking all 750mg at once, would like take it in the morning. Second, with such regular high daily dosing you are going to want to take TMG, which replenishes the methyl groups that are burned up through the process (methylation). 

I think if you try these 2 things you will find your issues go away.

Welcome to the group. Please keep us informed of your experience.


 

Thank you!

I do take the nmn first thing in the morning, and always supplement 1:1 with TMG.

I still get sleep disturbances after about 14 days, even on a low dosage of 300mg.
 

 

canadahealthy wrote: ↑Mon Dec 06, 2021 9:43 am

soniad wrote: ↑Fri Dec 03, 2021 3:18 pm

NewLifeScience wrote: ↑Fri Dec 03, 2021 7:41 am There are a couple of things I have observed and I hope this helps.

First, i take any NMN product well before supper and if i was taking all 750mg at once, would like take it in the morning. Second, with such regular high daily dosing you are going to want to take TMG, which replenishes the methyl groups that are burned up through the process (methylation). 

I think if you try these 2 things you will find your issues go away.

Welcome to the group. Please keep us informed of your experience.




 

Thank you!

I do take the nmn first thing in the morning, and always supplement 1:1 with TMG.

I still get sleep disturbances after about 14 days, even on a low dosage of 300mg.
 



 

That is unfortunate. My thoughts lead me to suggest perhaps going down to about 200mg or even 150mg and trying that level for a while. NR is also available and you may find less overall stimulation from taking it.

NMN stands apart and pretty much on its own for what it does... but the NR substitute and possibly daily use of NAD+ may be an option if you can't lower your sensitivity over time. 

I definitely could not take NMN in the evening for the first six months, but have no issues  now.


 

soniad wrote: ↑Thu Dec 02, 2021 8:32 pm Hi everyone,

I'm new to this forum and would like some advice regarding NMN supplements.

I'm a 137lb 53YO woman.

I have made a couple of attempts to take NMN. My longevity doctor told me that I should take 1 gram nmn per day.

My first attempt bombed after about 10 days - I got to 750mg and then crashed and burned....it ruined my sleep (could not fall asleep and then waking during the night for2 hours), plus I felt very depressed.

I later read that it can deplete methyl groups, so I decided to go slowly and add a TMG supplement. My doctor says I need to take at least 500mg to get any benefit, but I'm having trouble getting to anywhere near that amount.

The second time  around, I started with 50 mg and slowly increased to 300mg over 14 days I also added TMG at a 1:1 ratio.

Things were going fine until 2 days ago when I noticed sleep disturbances coming back. I also get occasional back pain and tried changing my mattress just to make sure everything is okay. I was able to change it with the help of a mattress lifter that was gifted to me. (I always take NMN in the morning)

I've read in a few places here that some people who found it affected sleep switched to NAD+.

I'm wondering if anyone could provide some recommendations for which form may benefit me given that NMN appears to give me side effects?

I am in Australia so we don't have any sublingual products available (that I know of), so far I can only find nmn. If I felt it would work I'd be willing to purchase from overseas.

Any advice would be greatly appreciated

thanks