https://onlinelibrary.wiley.com/doi/ful ... acel.13039
These results underscore the benefits of PRT in older adults, but metformin negatively impacts the hypertrophic response to resistance training in healthy older individuals.
Kind of confirmed that it is bad to combine metformin and exercise
Exercise ⇒ Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
Ph.D. student at Harvard Medical School, doing research on aging
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Re: Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
Very Interesting and a good read. I was proposing a pitch to my GP to prescribe me metformin but I am heavy into PRT and see this as a detriment now according to this study. I believe the best approach is keep my blood sugar levels low with diet for now.
thanks!
thanks!
Re: Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
I see people theorizing about alternating workouts and metformin, but I’m curious how much separation there needs to be between a metformin dose and a workout.
Re: Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
The short answer is we don't know yet. But I think you should consider metformin as a mimetic of exercising, it mimics the benefit of exercise through activating AMPK and cheating your body that you are short of energy. If you can exercise intensively every day, you can not benefit much from it and you don't actually need it. If you are obese and sedentary, you might need it and take it when you are not able to exercise.
But don't intentionally stop exercising just for taking metformin. Exercise is better, metformin is just a weaker mimetic with side effects.
Ph.D. student at Harvard Medical School, doing research on aging
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- Posts: 247
- Joined: Wed Aug 21, 2019 6:33 pm
- Location: Port Elgin, ON, Canada
Re: Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
There is also a landslide of other benefits that come with PRT than just muscle hypertrophy.
PRT is clearly the the better choice of the two if possible.
PRT is clearly the the better choice of the two if possible.
Re: Clinical trial: Metformin blunts muscle hypertrophy in response to PRT training in older adults
I wonder how many of the participants have been adding B12 supplements to their dietAlbertY wrote: ↑Fri Sep 27, 2019 12:17 pm https://onlinelibrary.wiley.com/doi/ful ... acel.13039
These results underscore the benefits of PRT in older adults, but metformin negatively impacts the hypertrophic response to resistance training in healthy older individuals.
Kind of confirmed that it is bad to combine metformin and exercise