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Trigonelline promotes cellular NAD⁺ production differently than other precursors such as NMN or NR.
Advantages include:
- Exceptional stability in bloodstream
- Slow release into target tissues
- Non-flushing
- Protected against digestion in the stomach
- Shown to increase NAD⁺ directly in muscle (unlike Niacin, NMN or NR)
Trigonelline (methylated niacin) is an NAD⁺ precursor that promotes NAD⁺ production in muscle cells, a property not observed in other NAD⁺ boosters like NMN or NR.
It accomplishes this through conversion in the Preiss-Handler pathway, unlike other NAD⁺ precursors which utilize the Salvage pathway.
Its innate bioavailable structure allows it to survive digestion, cross the blood-brain barrier, and directly stimulate NAD⁺ production in muscle, brain, and other tissues.
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
These products are not intended to diagnose, treat, cure or prevent any disease.
Consistent Trigonelline use can elevate NAD⁺ levels to support critical cellular functions including energy production, DNA repair, and cellular signaling:
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Enhanced NAD⁺ Synthesis: Promotes NAD⁺ production via the Preiss-Handler pathway, essential for cellular energy and repair.
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Cognitive Support: Crosses the blood-brain barrier, supporting cognitive function and protecting against age-related cognitive decline through protection of NAD⁺ stores in neurons.
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Metabolic Regulation: Acts as a methyl donor in one-carbon metabolism, supporting methylation processes crucial for energy production and genetic expression.
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Cardiovascular Health: Promotes the integrity of blood vessels and heart muscle, supporting endothelial function and circulatory health.
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DNA Repair: Encourages cellular repair mechanisms and maintains DNA integrity, helping prevent mutations and supporting natural defenses against environmental stress.
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Muscle Health: Protects against muscle loss and promotes muscle strength, crucial for maintaining physical fitness and metabolic health with aging.
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Glucose and Lipid Management: Enhances insulin sensitivity and glucose uptake, stabilizing blood glucose levels. Modulates lipid metabolism by inhibiting lipogenic enzymes and promoting lipoprotein lipase activity, improving lipid profiles.
These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
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Learn more about how Trigonelline works below:
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Why Choose Trigonelline?
This methylated form of the B vitamin Niacin offers unique NAD⁺ supporting benefits beyond what precursors like NMN or NR can provide, such as stability in circulation and promoting NAD⁺ synthesis directly in muscle tissue.
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Skin and Body Essentials Question
USER QUESTION
Hi Team,
I recently bought the Skin and Body Essentials powder. One thing I noticed is that it contains 12g of protein. I bought this more for the collagen and electrolytes (the protein wasn’t as apparent in your marketing for it).
The thing is, I already take a whey protein powder which is 24g of protein. My intention was to mix the protein powder with this powder and have it after my daily exercise…. But I think 36g of protein in one hit is too much.
Can you tell me what type of protein you actually use?
Also, do you recommend this is taken before or after exercise?
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