Research

Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects โThe aim of this study was to confirm the safety of our manufactured NMN...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...

NR Improved Brain and Blood Vessel Health in Ad...
Key Points Blood vessel function improved after 4 weeks of NR supplementation Brain blood flow increased in areas linked to memory and decision-making Participants showed modest gains in cognitive tests,...
NR Improved Brain and Blood Vessel Health in Ad...
Key Points Blood vessel function improved after 4 weeks of NR supplementation Brain blood flow increased...

Safety of IV Nicotinamide Riboside at Different...
Key Points IV NR was well tolerated at doses up to 450 mg/kg High doses (600 mg/kg) caused negative effects, including cardiovascular, liver, and kidney damage Increasing Doses of IV...
Safety of IV Nicotinamide Riboside at Different...
Key Points IV NR was well tolerated at doses up to 450 mg/kg High doses (600...

NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...

Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: ย Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers,...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: ย Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging...

NR Improved Heart Health in Adults
Key Points NR supplementation significantly increased NAD+ levels Blood pressure was reduced in the NR group The health and function of blood vessels improved in the group taking NR Study...
NR Improved Heart Health in Adults
Key Points NR supplementation significantly increased NAD+ levels Blood pressure was reduced in the NR group...

NMN Reversed Age-Related Metabolic Dysfunction ...
Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced The metabolism of inflammatory fats was alteredย Study Overview Aging was modeled in mice...
NMN Reversed Age-Related Metabolic Dysfunction ...
Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced...

NR Boosts Fat-Burning Activity in Obese Mice
What is Brown Fat and Why is it Important? Brown fat, or brown adipose tissue (BAT), is a special type of body fat that burns energy to produce heat -...
NR Boosts Fat-Burning Activity in Obese Mice
What is Brown Fat and Why is it Important? Brown fat, or brown adipose tissue (BAT),...

Efficacy of Liposomal Delivery Systems in Nutra...
Liposomal Delivery: What It Is and Why It Matters When it comes to supplements, taking them is one thing, but being able to actually absorb and use them is another....
Efficacy of Liposomal Delivery Systems in Nutra...
Liposomal Delivery: What It Is and Why It Matters When it comes to supplements, taking them...

Navigating Hormonal Transitions: Womenโs Health...
Understanding Hormonal Shifts During perimenopause and menopause, your body goes through a bit of a hormonal roller coaster, especially when it comes to estrogen and progesterone. Estrogen, a sex hormone...
Navigating Hormonal Transitions: Womenโs Health...
Understanding Hormonal Shifts During perimenopause and menopause, your body goes through a bit of a hormonal...

The Forgotten Foundations: Sleep, Sunlight, and...
Effects of Aging on Your Biological Clock Your circadian rhythm is basically your bodyโs internal clock, guiding the natural 24-hour cycle of sleep, wakefulness, and a variety of physiological processes....
The Forgotten Foundations: Sleep, Sunlight, and...
Effects of Aging on Your Biological Clock Your circadian rhythm is basically your bodyโs internal clock,...
Variations in Nicotinamide Metabolism Impacts P...
This study evaluated how well nicotinamide (NAM) reaches the brain and its effect on phosphorylated tau (pTau231), a key protein linked to Alzheimerโs disease (AD). Key Points:ย Some participants had...
Variations in Nicotinamide Metabolism Impacts P...
This study evaluated how well nicotinamide (NAM) reaches the brain and its effect on phosphorylated tau...