Scientific Evidence Library
Featured Articles
Want to stay up to date on the latest in longevity science?
Join our research-focused newsletter for simple, timely insights.
Scientific Evidence Library
NMN Supports Healthy Blood Pressure in Adu...
Key Points NMN significantly reduced diastolic blood pressure (DBP) Systolic blood pressure (SBP) showed a non-significant reduction Adults 60+ saw a ~4 mmHg reduction in SBP NMN was well tolerated,...
NMN Supports Healthy Blood Pressure in Adults: ...
Key Points NMN significantly reduced diastolic blood pressure (DBP) Systolic blood pressure (SBP) showed a non-significant...
NMN & NR Increase NAD+ in Blood and Brain
Key Points NAD+ blood levels steadied after 2 weeks Brain NAD+ increased after 4 weeks Elevated NAD+ declined gradually after stopping "Both NR and NMN showed excellent tolerability with no...
NMN & NR Increase NAD+ in Blood and Brain
Key Points NAD+ blood levels steadied after 2 weeks Brain NAD+ increased after 4 weeks Elevated...
NMN Rescued Brain Aging and Strengthened t...
Key Points NMN improved movement and memory in aging mice Brain inflammation and oxidative stress were reduced Markers of cellular aging and neuronal death declined Mitochondrial signaling (Sirt1/AMPK/PGC-1Ξ±) increased Gut...
NMN Rescued Brain Aging and Strengthened the Gu...
Key Points NMN improved movement and memory in aging mice Brain inflammation and oxidative stress were...
PQQ, NMN, and Interoception After Exhausti...
Key Points "Body Listening" was the only interoceptive domain that significantly improved. Combined PQQ + NMN did not outperform PQQ alone. NMN alone did not significantly change interoception. Across all...
PQQ, NMN, and Interoception After Exhaustive Ex...
Key Points "Body Listening" was the only interoceptive domain that significantly improved. Combined PQQ + NMN...
Combined EGCG NAD+ Precursors Enhance Hair...
Key Points MiAc shampoo and scalp tonic significantly increased hair count Raised cellular energy (ATP) to 132.6% in human cells Increased mitochondrial content to 112.2% Upregulated mitochondrial regulators Enhanced key...
Combined EGCG NAD+ Precursors Enhance Hair Grow...
Key Points MiAc shampoo and scalp tonic significantly increased hair count Raised cellular energy (ATP) to...
NMN Reduces Exercise-Induced Inflammation ...
Key Points NMN reduced inflammatory signals after intense exercise Early muscle repair signaling was slightly delayed Exercise caused a rapid 171% rise in muscle mitochondria NMN prevented this mitochondrial increase...
NMN Reduces Exercise-Induced Inflammation and R...
Key Points NMN reduced inflammatory signals after intense exercise Early muscle repair signaling was slightly delayed...
NMN Slows Aging Declines in Mice
Key Points NMN was absorbed within minutes Insulin sensitivity and fat cell profiles improved Age-related weight gain was suppressed NMN improved eye function and bone density Mice showed increased energy...
NMN Slows Aging Declines in Mice
Key Points NMN was absorbed within minutes Insulin sensitivity and fat cell profiles improved Age-related weight...
NMN Protects Against Alcohol Liver Disease...
Key Points NMN restored NAD+ balance and activated SIRT1 Markers of oxidative damage decreased Damaged liver structure improved NMN reduced inflammatory proteins Stronger results seen at higher doses Study Overview...
NMN Protects Against Alcohol Liver Disease in Mice
Key Points NMN restored NAD+ balance and activated SIRT1 Markers of oxidative damage decreased Damaged liver...
NMN Improves Symptoms and Extends Lifespan...
Key Points NMN extended lifespan in mice by up to 8 weeks Restored NAD+ levels in cells and tissues Improved mitochondrial function and antioxidant defenses Reduced cellular senescence and DNA...
NMN Improves Symptoms and Extends Lifespan in a...
Key Points NMN extended lifespan in mice by up to 8 weeks Restored NAD+ levels in...
NMN Improves Sleep Quality in Middle-Aged ...
Key Points NMN improved the time to fall asleep and daytime function Deep sleep and REM sleep increased, with fewer nighttime awakenings People taking NMN reported better overall sleep Overall...
NMN Improves Sleep Quality in Middle-Aged and O...
Key Points NMN improved the time to fall asleep and daytime function Deep sleep and REM...
NMN and NR Outperform NAM at Raising NADβΊ ...
Key Points NR and NMN doubled circulating NAD+ levels, NAM did not NMN and NR performed significantly & comparably NAM increased homocysteine levels, reflecting increased methylation demand Degradation of NMN...
NMN and NR Outperform NAM at Raising NADβΊ Level...
Key Points NR and NMN doubled circulating NAD+ levels, NAM did not NMN and NR performed...
NMN Protects Blood-Brain Barrier From Injury
Key Points NMN significantly restored brain NADβΊ levels Improved BBB structure and reduced permeability NMN improved behavioral outcomes Mitochondrial function was improved Overview of Methods Adult male mice were assigned...
NMN Protects Blood-Brain Barrier From Injury
Key Points NMN significantly restored brain NADβΊ levels Improved BBB structure and reduced permeability NMN improved...