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Research
Liposomal NAD+ Enhances Delivery and Reduces Ag...
Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7% Decreased key aging markers (p16 and p21) Improved cell survival Delivered 30% more NAD+...
Liposomal NAD+ Enhances Delivery and Reduces Ag...
Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7%...
NMN Outperforms NR and Other NAD+ Precursors in...
Key Points NMN outperformed NR and NAM, triggering stronger skin cell protection Cellular aging slowed through improved energy and repair activity Mitochondrial health and energy production were preserved Collagen production...
NMN Outperforms NR and Other NAD+ Precursors in...
Key Points NMN outperformed NR and NAM, triggering stronger skin cell protection Cellular aging slowed through...
Why We Don’t Offer NMNH Products
NMNH & NRH: Powerful But Complex Both NMNH and NRH are reduced forms of the more widely known counterparts. This structural difference means they enter the NAD+ pathway in a...
Why We Don’t Offer NMNH Products
NMNH & NRH: Powerful But Complex Both NMNH and NRH are reduced forms of the more...
Emerging Strategies, Applications, and Challeng...
Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a master regulator of health, supporting DNA repair, epigenetic programming, immune responses, and mitochondrial function....
Emerging Strategies, Applications, and Challeng...
Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a...
Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have been leading choices for raising NAD+ levels. Their popularity stems from the limitations of...
Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects “The aim of this study was to confirm the safety of our manufactured NMN...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers,...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging...
Latest Breakthroughs in NAD+ Research: What the...
NMN, NR, and NAD+: A Brief Refresher NAD+ is an important molecule found in virtually every cell of your body, which is required for DNA repair, energy production, metabolism, and...
Latest Breakthroughs in NAD+ Research: What the...
NMN, NR, and NAD+: A Brief Refresher NAD+ is an important molecule found in virtually every...
NMN Transporters and eNAMPT: Key Regulators of ...
“With these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is now proposed, featuring multi-layered feedback loops mediated by NMN and eNAMPT for mammalian aging...
NMN Transporters and eNAMPT: Key Regulators of ...
“With these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is...
A Novel NAD+ Precursor (NRH) Improves Glucose a...
“To our knowledge, this is the first report showing that NRH can reach multiple tissues intact and provide a broad spectrum of effects through potent NAD+ enhancement and subsequent SIRT...
A Novel NAD+ Precursor (NRH) Improves Glucose a...
“To our knowledge, this is the first report showing that NRH can reach multiple tissues intact...
Increased NAD+ Turnover, Minor Decline in Level...
“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation, supporting the rationale for NAD+ augmentation to attenuate disease severity.”
Increased NAD+ Turnover, Minor Decline in Level...
“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation,...