Research

article-page-carousel-item--Safety Trial Favors High Dose NMN

Safety Trial Favors High Dose NMN

Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects โ€œThe aim of this study was to confirm the safety of our manufactured NMN...

Safety Trial Favors High Dose NMN

Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...

article-page-carousel-item--NAD+ as a Multi-Target Therapy for Neurodegenerative Diseases: A Review of the Evidence

NAD+ as a Multi-Target Therapy for Neurodegener...

Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...

NAD+ as a Multi-Target Therapy for Neurodegener...

Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...

article-page-carousel-item--Mouse Study Shows Organ-Specific Effects of NAD+ Modulation on Aging

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: ย  Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers,...

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: ย  Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging...

article-page-carousel-item--Latest Breakthroughs in NAD+ Research: What the Science Says in 2025

Latest Breakthroughs in NAD+ Research: What the...

NMN, NR, and NAD+: A Brief Refresher NAD+ is an important molecule found in virtually every cell of your body, which is required for DNA repair, energy production, metabolism, and...

Latest Breakthroughs in NAD+ Research: What the...

NMN, NR, and NAD+: A Brief Refresher NAD+ is an important molecule found in virtually every...

article-page-carousel-item--NMN Transporters and eNAMPT: Key Regulators of NAD+ Balance in Aging

NMN Transporters and eNAMPT: Key Regulators of ...

โ€œWith these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is now proposed, featuring multi-layered feedback loops mediated by NMN and eNAMPT for mammalian aging...

NMN Transporters and eNAMPT: Key Regulators of ...

โ€œWith these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is...

article-page-carousel-item--A Novel NAD+ Precursor (NRH) Improves Glucose and Fat Metabolism in Obese Mice

A Novel NAD+ Precursor (NRH) Improves Glucose a...

โ€œTo our knowledge, this is the first report showing that NRH can reach multiple tissues intact and provide a broad spectrum of effects through potent NAD+ enhancement and subsequent SIRT...

A Novel NAD+ Precursor (NRH) Improves Glucose a...

โ€œTo our knowledge, this is the first report showing that NRH can reach multiple tissues intact...

article-page-carousel-item--Increased NAD+ Turnover, Minor Decline in Levels in COVID-19 Patients

Increased NAD+ Turnover, Minor Decline in Level...

โ€œNAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation, supporting the rationale for NAD+ augmentation to attenuate disease severity.โ€

Increased NAD+ Turnover, Minor Decline in Level...

โ€œNAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation,...

article-page-carousel-item--NR IV Exhibits Faster NAD+ Rise and Better Tolerability in Humans

NR IV Exhibits Faster NAD+ Rise and Better Tole...

โ€œIn comparison to NAD+ IV, NR IV was infused faster, and the infusion experience was more tolerable.โ€

NR IV Exhibits Faster NAD+ Rise and Better Tole...

โ€œIn comparison to NAD+ IV, NR IV was infused faster, and the infusion experience was more...

article-page-carousel-item--NAD+ Nanoparticle Injection Decreased Blood Vessel Damage In Rats

NAD+ Nanoparticle Injection Decreased Blood Ves...

A new study found injection of NAD+ using a novel liposome-like nano-particle carrier reduced overgrowth of smooth muscle cells and improved blood vessel healing in rats with narrowed arteries.

NAD+ Nanoparticle Injection Decreased Blood Ves...

A new study found injection of NAD+ using a novel liposome-like nano-particle carrier reduced overgrowth of...

article-page-carousel-item--Neuroprotective Effects of NAD+ Nasal Spray

Neuroprotective Effects of NAD+ Nasal Spray

"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to brain tissues, thereby circumventing the hepatic first-pass metabolism and gastric degradation and allowing fast...

Neuroprotective Effects of NAD+ Nasal Spray

"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to...

article-page-carousel-item--NAD+ Injections Guard Against Heart Failure in Rats and Beagles

NAD+ Injections Guard Against Heart Failure in ...

โ€œThis study, involving rat and beagle MI-induced HF models, indicated that NAD+ significantly improves myocardial hypertrophy and cardiac function, inhibits myocardial fibrosis, and reduces the myocardial infarction rate.โ€

NAD+ Injections Guard Against Heart Failure in ...

โ€œThis study, involving rat and beagle MI-induced HF models, indicated that NAD+ significantly improves myocardial hypertrophy...

article-page-carousel-item--Extracellular NAD+ Suppresses Inflammatory Response

Extracellular NAD+ Suppresses Inflammatory Resp...

A recent literature review explored the impact of extracellular NAD+ on the inflammatory response.

Extracellular NAD+ Suppresses Inflammatory Resp...

A recent literature review explored the impact of extracellular NAD+ on the inflammatory response.