A groundbreaking new study from UC Berkeley reports that combining oxytocin (OT) with an Alk5 inhibitor (A5i) dramatically extended lifespan and healthspan in old frail male mice - showing the...
NAD+ Decline: Why Supplementation Matters NAD+ is a critical coenzyme in hundreds of cellular processes, including energy production (glycolysis, citric acid cycle, oxidative phosphorylation), DNA repair through PARP activation, sirtuin-mediated...
“Depletion of nicotinamide adenine dinucleotide (NAD)+ has been reported in patients with WS, suggesting a key role in the pathogenesis of WS.” Key Points No serious adverse effects reported NR...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
Key Points Researchers found that NMN offers several important benefits for skin exposed to UVB: Helped maintain healthy skin structure after UVB exposure Reduced inflammation and oxidative stress Supported liver...
Key Points: NMN increased NAD+ blood levels Physical performance steadily improved in the NMN groups Quality of life was enhanced No effects on insulin resistance were observed Clinical Trial Evaluates...
Green Tea Extract, in its concentrated form, has shown significant potential in addressing age-related concerns related to heart health, cognitive function, and metabolism.
This study found that the continued administration of Green Tea Catechin (EGCG) improves the lifespan, cellular health, and cell waste clearance in aging mice.
“These data from a community-based sample demonstrate that SWS percentage declines over time in adults 60 years and older and that greater declines are associated with the risk of future...
This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial function in the skeletal muscle.