Scientific Evidence Library

article-page-carousel-item--Long Term NMN Use Extends Lifespan and Healthspan in Mice with Sex-Specific Effects

Long Term NMN Use Extends Lifespan and Healthsp...

Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...

Long Term NMN Use Extends Lifespan and Healthsp...

Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male...

article-page-carousel-item--NMN Human Trial Shows Increased Endurance, NAD+ Blood Levels, and Benefits to Bioage

NMN Human Trial Shows Increased Endurance, NAD+...

Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels are known to decline with age, affecting longevity and age-related health conditions, better known...

NMN Human Trial Shows Increased Endurance, NAD+...

Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels...

article-page-carousel-item--Dogs and Humans Share Same Benefits from NMN Supplementation

Dogs and Humans Share Same Benefits from NMN Su...

Dog and human NAD+ levels both decline with age Dogs have the same problem as humans in that their NAD+ levels decline with age in various critical organs, such as...

Dogs and Humans Share Same Benefits from NMN Su...

Dog and human NAD+ levels both decline with age Dogs have the same problem as humans...

article-page-carousel-item--NMN restores kidney function and prevents kidney damage

NMN restores kidney function and prevents kidne...

Use of NMN supplements was shown to activate Sirtuin-1, one of the body’s self repair enzymes, to repair kidney damage and restore kidney function in mice. (1) Β 

NMN restores kidney function and prevents kidne...

Use of NMN supplements was shown to activate Sirtuin-1, one of the body’s self repair enzymes,...

article-page-carousel-item--Increasing NMN Transporter in the Brain Reduces Age-Related Muscle Decline

Increasing NMN Transporter in the Brain Reduces...

Doubling Slc128a Dramatically Improved Muscle Strength and Endurance It’s known that NMN transporters like Slc128a help to maintain NAD+ levels as we age. This caused researchers to speculate what may...

Increasing NMN Transporter in the Brain Reduces...

Doubling Slc128a Dramatically Improved Muscle Strength and Endurance It’s known that NMN transporters like Slc128a help...

article-page-carousel-item--Heart Disease Related to Accumulation of DNA Damage and Oxidative Stress

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...

article-page-carousel-item--Inhibition of CD38 Increases NAD+ Levels, Extends Life and Healthspan in Mice

Inhibition of CD38 Increases NAD+ Levels, Exten...

Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant increases in lifespan and healthspan in mice.

Inhibition of CD38 Increases NAD+ Levels, Exten...

Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels...

article-page-carousel-item--Newly Found Benefits of Resveratrol in Health and Anti-aging

Newly Found Benefits of Resveratrol in Health a...

Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body's own self-repair proteins, called sirtuins. When sirtuins are activated,...

Newly Found Benefits of Resveratrol in Health a...

Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance...

article-page-carousel-item--Increased NAD+ in Bloodstream of Nursing Mice Results in Healthier, Stronger, Smarter Offspring

Increased NAD+ in Bloodstream of Nursing Mice R...

These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...

Increased NAD+ in Bloodstream of Nursing Mice R...

These improvements in health and behavior persisted for the length of the study, which was 90...