Scientific Evidence Library
Featured Articles
Want to stay up to date on the latest in longevity science?
Join our research-focused newsletter for simple, timely insights.
Scientific Evidence Library
NMN Improves Brain Recovery and Survival A...
Key Points Post-arrest NMN rapidly restored brain NADβΊ levels ATP levels rose nearly 40% vs. controls Neurological scores were significantly improved at 48 hours Seven-day survival nearly tripled NMN reduced...
NMN Improves Brain Recovery and Survival After ...
Key Points Post-arrest NMN rapidly restored brain NADβΊ levels ATP levels rose nearly 40% vs. controls...
NAD+ and Brain Health: Neuroprotective Mec...
Nicotinamide adenine dinucleotide (NAD+) has become one of the most buzzworthy supplements on the market, thanks to its powerful neuroprotective properties and potential to boost brain health. In fact, NAD+...
NAD+ and Brain Health: Neuroprotective Mechanis...
Nicotinamide adenine dinucleotide (NAD+) has become one of the most buzzworthy supplements on the market, thanks...
Nicotinamide Riboside Repaired Brain Damag...
Key Points NR treatment increased brain NADβΊ and NMN levels. Enhanced memory performance Reduced mitochondrial damage and preserved structure Normalized ATP production and improved energy balance Suppressed brain cell inflammation...
Nicotinamide Riboside Repaired Brain Damage and...
Key Points NR treatment increased brain NADβΊ and NMN levels. Enhanced memory performance Reduced mitochondrial damage...
Resveratrol and NMN Restore Brain Metaboli...
Key Points Wood smoke impaired brain chemistry and behavior Resveratrol + NMN provided the strongest protection Combination therapies showed mixed results NAD+ proved to be a key target for protecting...
Resveratrol and NMN Restore Brain Metabolism an...
Key Points Wood smoke impaired brain chemistry and behavior Resveratrol + NMN provided the strongest protection...
NMN Improves Movement and Brain Health in ...
Key Points: NMN restored NAD+ levels and improved motor performance in Parkinsonβs disease (PD) model mice. It reduced inflammation, prevented synaptic loss, and lowered harmful brain immune activity (gliosis). The...
NMN Improves Movement and Brain Health in a Par...
Key Points: NMN restored NAD+ levels and improved motor performance in Parkinsonβs disease (PD) model mice....
NAD+ as a Multi-Target Therapy for Neurode...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...
Trigonelline Improves Healing and Reduces ...
βTrigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme complexes, and modulating apoptotic and neurotrophic factors.β
Trigonelline Improves Healing and Reduces Damag...
βTrigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme...
NMN Enhanced Mitochondrial Stress Response...
βWe combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by which NAD+-boosting agent nicotinamide mononucleotide (NMN) regulates MSR in AD models.β
NMN Enhanced Mitochondrial Stress Response and ...
βWe combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by...
NMN Offers More Protection Than NR in Frie...
Key Points: NMN and NR provided several benefits in mice with FRDA and highlighted key differences between the two treatments: NMN more effectively restored NAD+ levels in the heart than...
NMN Offers More Protection Than NR in Friedreic...
Key Points: NMN and NR provided several benefits in mice with FRDA and highlighted key differences...
NMN Enhances Cellular Protection and Cogni...
Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory Reduced neuronal injury Promoted clearance of abnormal tau protein Activated autophagy Enhanced antioxidant defense...
NMN Enhances Cellular Protection and Cognitive ...
Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory...
Berberine Improves Motor Function in a Rat...
Key Points: Berberine supplementation displayed therapeutic benefits for managing Parkinsonβs disease symptoms: Improved motor function and coordination Reduced oxidative stress and enhanced antioxidant defenses Restored mitochondrial function Decreased neuroinflammation and...
Berberine Improves Motor Function in a Rat Mode...
Key Points: Berberine supplementation displayed therapeutic benefits for managing Parkinsonβs disease symptoms: Improved motor function and...
NMN Nanoparticles Outperform Free NMN for ...
This study investigated the potential of NMN-loaded nanoparticles to prevent age-related decline in a model of aging mice.
NMN Nanoparticles Outperform Free NMN for Anti-...
This study investigated the potential of NMN-loaded nanoparticles to prevent age-related decline in a model of...