Scientific Evidence Library

article-page-carousel-item--Long Term NMN Use Extends Lifespan and Healthspan in Mice with Sex-Specific Effects

Long Term NMN Use Extends Lifespan and Healthsp...

Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...

Long Term NMN Use Extends Lifespan and Healthsp...

Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male...

article-page-carousel-item--Slc12a8 Transporter is Key for Efficacy of NMN in Septic Mice

Slc12a8 Transporter is Key for Efficacy of NMN ...

Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport through the Slc12a8 transporter.

Slc12a8 Transporter is Key for Efficacy of NMN ...

Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport...

article-page-carousel-item--NR Shows Ability to Promote DNA Repair and Increase Lifespan by 25% in Mice

NR Shows Ability to Promote DNA Repair and Incr...

Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this study were shown to have an effect on lifespan in mice engineered to age...

NR Shows Ability to Promote DNA Repair and Incr...

Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this...

article-page-carousel-item--NAD+ Reduces Mutations and Incidence of Skin Cancer

NAD+ Reduces Mutations and Incidence of Skin Ca...

NMN and NR lead to greater increases in NAD+ than NAM It has been well established that the molecules NMN and NR lead to greater increases in NAD+ levels than...

NAD+ Reduces Mutations and Incidence of Skin Ca...

NMN and NR lead to greater increases in NAD+ than NAM It has been well established...

article-page-carousel-item--Fisetin Effectively Eliminates Senescent Cells and Restores Stem Cells

Fisetin Effectively Eliminates Senescent Cells ...

Since immune cells play such a critical role in keeping the population of senescent cells in check, senescent immune cells are a prime target of senolytic drugs. Fisetin has been...

Fisetin Effectively Eliminates Senescent Cells ...

Since immune cells play such a critical role in keeping the population of senescent cells in...

article-page-carousel-item--Heart Disease Related to Accumulation of DNA Damage and Oxidative Stress

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...