Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...
This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation, mitochondrial function, and survival in mice.
“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”
This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing inflammation and modulating levels of proteins associated with cartilage health.
Reduction in All-Cause Mortality Correlates with Green Tea Consumption. Numerous large-scale studies with over 300,000+ participants have demonstrated that green tea consumption is associated with a significant decrease in all-cause...
Dog and human NAD+ levels both decline with age Dogs have the same problem as humans in that their NAD+ levels decline with age in various critical organs, such as...
Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this study were shown to have an effect on lifespan in mice engineered to age...
Use of NMN supplements was shown to activate Sirtuin-1, one of the body’s self repair enzymes, to repair kidney damage and restore kidney function in mice. (1)
Doubling Slc128a Dramatically Improved Muscle Strength and Endurance It’s known that NMN transporters like Slc128a help to maintain NAD+ levels as we age. This caused researchers to speculate what may...
Scientists from Baylor College of Medicine in Houston studying glutathione precursors have demonstrated some of the best life extension results ever achieved in mice – increasing their lifespan by 24%.
Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body's own self-repair proteins, called sirtuins. When sirtuins are activated,...