Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--NAD+ Therapy Improves Cardiovascular Function in Heart Failure Patients

NAD+ Therapy Improves Cardiovascular Funct...

3 min

Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased NAD+ was well tolerated for heart disease patients Methods 180 adults with heart failure...

3 min

NAD+ Therapy Improves Cardiovascular Function i...

Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased...

article-page-carousel-item--Emerging Strategies, Applications, and Challenges of Targeting NAD⁺ in the Clinic: A Review

Emerging Strategies, Applications, and Cha...

11 min

Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a master regulator of health, supporting DNA repair, epigenetic programming, immune responses, and mitochondrial function....

11 min

Emerging Strategies, Applications, and Challeng...

Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a...

article-page-carousel-item--Nicotinamide Riboside Shows Promise in Treating Premature Aging in Humans

Nicotinamide Riboside Shows Promise in Tre...

3 min

β€œDepletion of nicotinamide adenine dinucleotide (NAD)+ has been reported in patients with WS, suggesting a key role in the pathogenesis of WS.” Key Points No serious adverse effects reported NR...

3 min

Nicotinamide Riboside Shows Promise in Treating...

β€œDepletion of nicotinamide adenine dinucleotide (NAD)+ has been reported in patients with WS, suggesting a key...

article-page-carousel-item--Safety Trial Favors High Dose NMN

Safety Trial Favors High Dose NMN

2 min

Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects β€œThe aim of this study was to confirm the safety of our manufactured NMN...

2 min

Safety Trial Favors High Dose NMN

Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...

article-page-carousel-item--Novel Delivery System Improves NMN Absorption in Mice

Novel Delivery System Improves NMN Absorpt...

4 min

β€œUpon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

4 min

Novel Delivery System Improves NMN Absorption i...

β€œUpon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN,...

article-page-carousel-item--NMN Reduces Heart Failure and Extends Lifespan in Mice

NMN Reduces Heart Failure and Extends Life...

3 min

β€œThese results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”

3 min

NMN Reduces Heart Failure and Extends Lifespan ...

β€œThese results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32...

article-page-carousel-item--NMN Improves Blood Pressure in Humans with Hypertension

NMN Improves Blood Pressure in Humans with...

5 min

β€œOverall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic...

5 min

NMN Improves Blood Pressure in Humans with Hype...

β€œOverall, the present study may shed new light on novel strategies in which NAD+ boosting therapy,...

article-page-carousel-item--Study Shows NMN Protects Against Lung Damage in Mice

Study Shows NMN Protects Against Lung Dama...

5 min

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

5 min

Study Shows NMN Protects Against Lung Damage in...

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure...