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Scientific Evidence Library
Study: NMN Reduced Heart Scarring in Diabe...
Key Points NMN reduced excess collagen buildup in the heart Mice showed improved cardiac function NMN reduced proteins involved in excess collagen buildup. NMN lowered oxidative stress in heart...
Study: NMN Reduced Heart Scarring in Diabetic Mice
Key Points NMN reduced excess collagen buildup in the heart Mice showed improved cardiac function...
NMN Improves Heart Stress Markers in Dogs
Key Points Several dogs showed lower heart stress marker levels after NMN. NMN's effects may relate to NAD⁺ energy metabolism and mitochondrial function. NT-proBNP changes varied by heart condition....
NMN Improves Heart Stress Markers in Dogs
Key Points Several dogs showed lower heart stress marker levels after NMN. NMN's effects may...
New Human Data Is Reshaping What We Know A...
The “Age-Related NAD⁺ Decline” Model Is Being Revisited Early human studies helped build the case for age-related NAD⁺ decline. Lower NAD⁺ levels in older adults were found using blood metabolomics....
New Human Data Is Reshaping What We Know About ...
The “Age-Related NAD⁺ Decline” Model Is Being Revisited Early human studies helped build the case for...
NAM Improves Retinal Function in Glaucoma
Key Points NAM strengthened optic nerve signals Retinal cell activity improved Eye pressure and structure remained stable Well tolerated with no serious adverse events Overview of Study Fifty-three adults with...
NAM Improves Retinal Function in Glaucoma
Key Points NAM strengthened optic nerve signals Retinal cell activity improved Eye pressure and structure remained...
NMN and NR Outperform NAM at Raising NAD⁺ ...
Key Points NR and NMN doubled circulating NAD+ levels, NAM did not NMN and NR performed significantly & comparably NAM increased homocysteine levels, reflecting increased methylation demand Degradation of NMN...
NMN and NR Outperform NAM at Raising NAD⁺ Level...
Key Points NR and NMN doubled circulating NAD+ levels, NAM did not NMN and NR performed...
Human Study: IV NAD+ Improves IVF Embryo Q...
Key Points NAD+ increased the number of mature eggs retrieved More eggs were successfully fertilized Number of top-quality (Grade A) embryos more than doubled Benefits observed in both younger (<35...
Human Study: IV NAD+ Improves IVF Embryo Quality
Key Points NAD+ increased the number of mature eggs retrieved More eggs were successfully fertilized Number...
NMN Doubles NAD+ in COVID-19 Hospitalizations
Key Points Blood NAD⁺ levels increased significantly NAD⁺ metabolites rose rapidly No impact was seen on kidney function Methods 42 adults hospitalized with COVID-19 and experiencing AKI were split into...
NMN Doubles NAD+ in COVID-19 Hospitalizations
Key Points Blood NAD⁺ levels increased significantly NAD⁺ metabolites rose rapidly No impact was seen on...
NMN Improves Brain Recovery and Survival A...
Key Points Post-arrest NMN rapidly restored brain NAD⁺ levels ATP levels rose nearly 40% vs. controls Neurological scores were significantly improved at 48 hours Seven-day survival nearly tripled NMN reduced...
NMN Improves Brain Recovery and Survival After ...
Key Points Post-arrest NMN rapidly restored brain NAD⁺ levels ATP levels rose nearly 40% vs. controls...
Nicotinamide Riboside Repaired Brain Damag...
Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage and preserved structure Normalized ATP production and improved energy balance Suppressed brain cell inflammation...
Nicotinamide Riboside Repaired Brain Damage and...
Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage...
NAD+ Accelerates Hearing Recovery
Key Points NAD+ led to greater hearing improvement and faster recovery Average hearing gain nearly doubled: +40.2 dB HL vs +23.1 dB HL (Hearing Levels) Word Recognition Score (WRS) reached...
NAD+ Accelerates Hearing Recovery
Key Points NAD+ led to greater hearing improvement and faster recovery Average hearing gain nearly doubled:...
NAD+ Therapy Improves Cardiovascular Funct...
Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased NAD+ was well tolerated for heart disease patients Methods 180 adults with heart failure...
NAD+ Therapy Improves Cardiovascular Function i...
Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased...
Liposomal NAD+ Enhances Delivery and Reduc...
Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7% Decreased key aging markers (p16 and p21) Improved cell survival Delivered 30% more NAD+...
Liposomal NAD+ Enhances Delivery and Reduces Ag...
Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7%...