Scientific Evidence Library

Want to stay up to date on the latest in longevity science?

Join our research-focused newsletter for simple, timely insights.

Scientific Evidence Library

article-page-carousel-item--Study: NMN Reduced Heart Scarring in Diabetic Mice

Study: NMN Reduced Heart Scarring in Diabe...

4 min

  Key Points NMN reduced excess collagen buildup in the heart Mice showed improved cardiac function NMN reduced proteins involved in excess collagen buildup. NMN lowered oxidative stress in heart...

4 min

Study: NMN Reduced Heart Scarring in Diabetic Mice

  Key Points NMN reduced excess collagen buildup in the heart Mice showed improved cardiac function...

article-page-carousel-item--NMN Improves Heart Stress Markers in Dogs

NMN Improves Heart Stress Markers in Dogs

3 min

  Key Points Several dogs showed lower heart stress marker levels after NMN. NMN's effects may relate to NAD⁺ energy metabolism and mitochondrial function. NT-proBNP changes varied by heart condition....

3 min

NMN Improves Heart Stress Markers in Dogs

  Key Points Several dogs showed lower heart stress marker levels after NMN. NMN's effects may...

article-page-carousel-item--New Human Data Is Reshaping What We Know About NAD⁺

New Human Data Is Reshaping What We Know A...

5 min

The “Age-Related NAD⁺ Decline” Model Is Being Revisited Early human studies helped build the case for age-related NAD⁺ decline. Lower NAD⁺ levels in older adults were found using blood metabolomics....

5 min

New Human Data Is Reshaping What We Know About ...

The “Age-Related NAD⁺ Decline” Model Is Being Revisited Early human studies helped build the case for...

article-page-carousel-item--NAM Improves Retinal Function in Glaucoma

NAM Improves Retinal Function in Glaucoma

3 min

Key Points NAM strengthened optic nerve signals Retinal cell activity improved Eye pressure and structure remained stable Well tolerated with no serious adverse events Overview of Study Fifty-three adults with...

3 min

NAM Improves Retinal Function in Glaucoma

Key Points NAM strengthened optic nerve signals Retinal cell activity improved Eye pressure and structure remained...

article-page-carousel-item--NMN and NR Outperform NAM at Raising NAD⁺ Levels in Humans

NMN and NR Outperform NAM at Raising NAD⁺ ...

4 min

Key Points NR and NMN doubled circulating NAD+ levels, NAM did not NMN and NR performed significantly & comparably NAM increased homocysteine levels, reflecting increased methylation demand Degradation of NMN...

4 min

NMN and NR Outperform NAM at Raising NAD⁺ Level...

Key Points NR and NMN doubled circulating NAD+ levels, NAM did not NMN and NR performed...

article-page-carousel-item--Human Study: IV NAD+ Improves IVF Embryo Quality

Human Study: IV NAD+ Improves IVF Embryo Q...

4 min

Key Points NAD+ increased the number of mature eggs retrieved More eggs were successfully fertilized Number of top-quality (Grade A) embryos more than doubled Benefits observed in both younger (<35...

4 min

Human Study: IV NAD+ Improves IVF Embryo Quality

Key Points NAD+ increased the number of mature eggs retrieved More eggs were successfully fertilized Number...

article-page-carousel-item--NMN Doubles NAD+ in COVID-19 Hospitalizations

NMN Doubles NAD+ in COVID-19 Hospitalizations

2 min

Key Points Blood NAD⁺ levels increased significantly NAD⁺ metabolites rose rapidly No impact was seen on kidney function Methods 42 adults hospitalized with COVID-19 and experiencing AKI were split into...

2 min

NMN Doubles NAD+ in COVID-19 Hospitalizations

Key Points Blood NAD⁺ levels increased significantly NAD⁺ metabolites rose rapidly No impact was seen on...

article-page-carousel-item--NMN Improves Brain Recovery and Survival After Cardiac Arrest

NMN Improves Brain Recovery and Survival A...

4 min

Key Points Post-arrest NMN rapidly restored brain NAD⁺ levels ATP levels rose nearly 40% vs. controls Neurological scores were significantly improved at 48 hours Seven-day survival nearly tripled NMN reduced...

4 min

NMN Improves Brain Recovery and Survival After ...

Key Points Post-arrest NMN rapidly restored brain NAD⁺ levels ATP levels rose nearly 40% vs. controls...

article-page-carousel-item--Nicotinamide Riboside Repaired Brain Damage and Improves Memory

Nicotinamide Riboside Repaired Brain Damag...

4 min

Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage and preserved structure Normalized ATP production and improved energy balance Suppressed brain cell inflammation...

4 min

Nicotinamide Riboside Repaired Brain Damage and...

Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage...

article-page-carousel-item--NAD+ Accelerates Hearing Recovery

NAD+ Accelerates Hearing Recovery

3 min

Key Points NAD+ led to greater hearing improvement and faster recovery Average hearing gain nearly doubled: +40.2 dB HL vs +23.1 dB HL (Hearing Levels) Word Recognition Score (WRS) reached...

3 min

NAD+ Accelerates Hearing Recovery

Key Points NAD+ led to greater hearing improvement and faster recovery Average hearing gain nearly doubled:...

article-page-carousel-item--NAD+ Therapy Improves Cardiovascular Function in Heart Failure Patients

NAD+ Therapy Improves Cardiovascular Funct...

3 min

Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased NAD+ was well tolerated for heart disease patients Methods 180 adults with heart failure...

3 min

NAD+ Therapy Improves Cardiovascular Function i...

Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased...

article-page-carousel-item--Liposomal NAD+ Enhances Delivery and Reduces Aging in Skin and Blood Vessel Cells

Liposomal NAD+ Enhances Delivery and Reduc...

5 min

Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7% Decreased key aging markers (p16 and p21) Improved cell survival Delivered 30% more NAD+...

5 min

Liposomal NAD+ Enhances Delivery and Reduces Ag...

Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7%...