EGCG from Green Tea Protects Motor Control and Mood in Mice

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In a mouse model of Parkinson's Disease, mice that were pretreated with EGCG showed the least damage to neurons, had higher mood stability, and maintained more motor movement control.

In this figure, the white bars represent the number of TH immune-positive cells, a measure of healthy dopamine-sensitive cells.

Mice with damaged brain cells (PFFs group) experienced a 58% decrease in dopamine-sensitive cells compared to healthy mice (Sham group), where the EGCG pretreatment group (EGCG+PFFs group) only experienced a 36% loss in these cells.

EGCG pretreatment prevented the accumulation of α-synuclein preformed fibrils, a type of protein associated with Parkinson’s Disease and known to severely impair brain function.

Liposomal Delivery

Traditional EGCG is poorly absorbed, only 5-10% is taken up after digestion; LIPO Green Tea solves this problem, and enhances bioavailability to over 90%.

STUDY: Trigonelline - An NAD+ precursor that improves muscle function during ageing

RESEARCH

A recent study has looked at how trigonelline, a compound found in certain foods, can improve overall muscle function as one ages.

The researchers found that trigonelline enhanced NAD+ levels in the body and mitigated age-related decline in muscle strength and endurance.

Heather Makar

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Heather L. Makar is a biologist, longevity futurist, TEDx speaker, and science writer focused on translating complex mechanisms of aging into strategies for healthspan extension. At Renue By Science, she leads research-driven content strategy that empowers readers to understand, optimize, and evolve their own biology. She brings a multidisciplinary perspective to health optimization, bridging natural medicine and cutting edge science to build actionable protocols that have tangible effects immediately and far into the future.