TMG Methylation Essentials combines five key nutrients - TMG, Zinc, Folate, B12, and B6 - in one synergistic blend, providing targeted support for healthy methylation.
TMG Methylation Essentials replaces our original TMG product which contained only TMG, as we wanted to provide comprehensive methylation support, with the convenience of one single product.Β
We're offering 20% off of TMG Methylation Essentials, with the code: TMG20SALE.Β
"Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease." (1)
TMG, Methylation and Aging
Trimethylglycine (TMG) is a molecule produced naturally in the body and it plays an important role in the DNA methylation process. Proper methylation is vital for healthy aging. (2) Research shows that methylation decreases as people age.
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Methylation issues can be caused by:
nutrient deficiencies
genetic mutations (MTHFR)
physical or environmental stressors
The process of methylation is complex, as the patterns of methylation change throughout your life.
"An abundance of evidence indicates that reversal of aberrant DNA methylation could be an effective strategy to suppress disease and promote longevity." (2)
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Ingredients to Support Methylation
Trimethyglycine (TMG): A methyl donor supporting optimal methylation pathways and enhancing mitochondrial function, while protecting cells against environmental stress. (3) β
Zinc: A vital cofactor for enzymes that contribute to the proper functioning of the antioxidant defense system. (4) β
Vitamin B12: Essential for energy production, and an important regulator of DNA methylation. (5) β
Vitamin B6: Involved in over 100 biochemical reactions, including neurotransmitter synthesis and mood regulation. It's been shown to reduce elevated homocysteine levels, often associated with illness.β
Folate: A key vitamin involved in DNA methylation, vital to breaking down homocysteine, an amino acid that can exert harmful effects in the body if it is present in high amounts.β
β These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
Acid-Resistant Enteric Capsules
ββReaching the small intestines intact is critical to maximize uptake. Our Acid-Resistant Enteric Capsules have been engineered to make it through the harsh, acidic environment of the stomach without being degraded. They release their payload only when they reach the alkaline environment of the small intestine.
My dad is trying to avoid taking metformin for newly diagnosed diabetes and is willing to try different things for three months to see if it helps. Has anyone had any issues with digestion while taking this? I have been doing some reading and I'm concerned about this potential side effect.
Heather L. Makar is a biologist, longevity futurist, TEDx speaker, and science writer focused on translating complex mechanisms of aging into strategies for healthspan extension. At Renue By Science, she leads research-driven content strategy that empowers readers to understand, optimize, and evolve their own biology. She brings a multidisciplinary perspective to health optimization, bridging natural medicine and cutting edge science to build actionable protocols that have tangible effects immediately and far into the future.
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