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The Complete Guide to Choosing Your Optima...
NAD+ Decline: Why Supplementation Matters NAD+ is a critical coenzyme in hundreds of cellular processes, including energy production (glycolysis, citric acid cycle, oxidative phosphorylation), DNA repair through PARP activation, sirtuin-mediated...
The Complete Guide to Choosing Your Optimal NMN...
NAD+ Decline: Why Supplementation Matters NAD+ is a critical coenzyme in hundreds of cellular processes, including...
Oral NAD+: Revisiting Assumptions about Ef...
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have been leading choices for raising NAD+ levels. Their popularity stems from the limitations of...
Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have...
NMN Transporters and eNAMPT: Key Regulator...
“With these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is now proposed, featuring multi-layered feedback loops mediated by NMN and eNAMPT for mammalian aging...
NMN Transporters and eNAMPT: Key Regulators of ...
“With these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is...
Niacin, NMN, and NR Are Not The Same
While all three precursors – Niacin, NR, and NMN – elevate NAD+ levels, their journeys within the body are distinct. Understanding these individual pathways is crucial, as they may have...
Niacin, NMN, and NR Are Not The Same
While all three precursors – Niacin, NR, and NMN – elevate NAD+ levels, their journeys within...
NMN Supplementation Does Not Lead to Axona...
This article delves into the scientific evidence concerning NMN, SARM1 activation, and their impact on axonal health.
NMN Supplementation Does Not Lead to Axonal Deg...
This article delves into the scientific evidence concerning NMN, SARM1 activation, and their impact on axonal...
Advancements in NAD+ Research
New research on NAD+ metabolism, NMN supplementation, and mitochondrial NAD+ levels was presented at the esteemed longevity conference, the Aging Research and Drug Discovery (ARDD) Meeting.
Advancements in NAD+ Research
New research on NAD+ metabolism, NMN supplementation, and mitochondrial NAD+ levels was presented at the esteemed...
Testing Reveals Poor Quality of NMN and Ot...
In October, 2021 Chromadex did a study on twenty-two NMN brands having the highest market share on Amazon and found that only 14% had NMN content at or above the...
Testing Reveals Poor Quality of NMN and Other S...
In October, 2021 Chromadex did a study on twenty-two NMN brands having the highest market share...
New Research with NMN by IV Shows Much Str...
We believe that liposomal delivery most closely mimics IV injection of NMN, as liposomes protect NAD+ metabolites from digestion and degradation in the stomach, liver, and bloodstream.
New Research with NMN by IV Shows Much Stronger...
We believe that liposomal delivery most closely mimics IV injection of NMN, as liposomes protect NAD+...
Why Dr. Sinclair takes NMN instead of NR
“NMN makes mice run further. Old mice can run 50% further, because they have better blood flow, better energy. NR at the same dose did not do that. In fact...
Why Dr. Sinclair takes NMN instead of NR
“NMN makes mice run further. Old mice can run 50% further, because they have better blood...
David Sinclair's Supplement Stack and Long...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field of longevity research. In a recent video, titled “Dr David Sinclair – Defeating Ageing...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the opposite of what you are trying to accomplish by taking NAD+ boosters. The body...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the...
Reduced Nicotinamide Mononucleotide - A Ta...
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are both well-known NAD+ precursors that can effectively increase NAD+ levels across multiple tissues. They are very similar to each other. In fact,...
Reduced Nicotinamide Mononucleotide - A Tale of...
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are both well-known NAD+ precursors that can effectively increase...