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90 Capsules Allergen-Free

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Serving size 1 capsule

Hesperidin (Liposomal)

Hesperidin (Liposomal)

Citrus-sourced inflammation and heart support
Regular price $39.95 USD
Sale price $39.95 USD Regular price

Hesperidin is a plant compound found in citrus fruits with anti-inflammatory and cardioprotective activity.† LIPO Hesperidin is designed to promote blood vessel function, balance inflammation, and support heart health.†

LIPO Hesperidin is also available in our combination product, Energizer AM.

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90 Capsules Allergen-Free

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Serving size 1 capsule

LIPO Hesperidin Details

Hesperidin is a flavonoid, a type of plant compound that has been shown to have a wide range of health benefits.†

It is found primarily in citrus fruits, such as oranges, lemons, grapefruit, and limes.†

Hesperidin exhibits anti-inflammatory and antioxidant activity, protecting cells from two key contributors to the onset of age-related and chronic conditions, inflammation, and oxidative stress.†

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Hesperidin is a flavonoid, a type of plant compound that has been shown to have a wide range of health benefits.†

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It is found primarily in citrus fruits, such as oranges, lemons, grapefruit, and limes.†

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Hesperidin exhibits anti-inflammatory and antioxidant activity, protecting cells from two key contributors to the onset of age-related and chronic diseases: inflammation and oxidative stress.†

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Many studies have demonstrated the potential health effects of Hesperidin:

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Heart Health: A meta-analysis of 13 studies reported that Hesperidin supplementation decreased blood cholesterol levels, the inflammatory molecule TNF-α, and systolic blood pressure.†

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Blood pressure: In a clinical trial, adults with type 2 diabetes showed significant improvements in blood pressure, inflammation, and total antioxidant capacity (a measure indicating the ability to neutralize harmful free radicals) after supplementing with Hesperidin for 6 weeks.†

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Inflammation: An evaluation of 18 clinical trials in a meta-analysis revealed Hesperidin reduced several markers of inflammation and the levels of MDA, a marker of damage to fat important for cell function and structure.†

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Blood Vessel Function: A 3-week clinical trial showed Hesperidin improved blood flow and reduced the levels of inflammatory markers in adults with metabolic syndrome.† In a trial with overweight men, drinking a glass of orange juice daily or supplementing with Hesperidin for four weeks improved blood flow after meals, indicating improved blood vessel function.†

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Standard Hesperidin does not dissolve easily after ingestion, resulting in a bioavailability of about 20%.† This means that about 20% of Hesperidin is absorbed and available for use in the body.† (1)  To address this issue, LIPO Hesperidin uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†

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Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream. 


This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.

The aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract or are simply not absorbed in the small intestine at all. The majority is excreted unused via the intestines or kidneys. 


Liposomal delivery offers a targeted and complete absorption of active ingredients with a delayed‑release effect, unlike all other nutrient delivery methods. This increased circulation time of key nutrients in the bloodstream significantly improves bioavailability. The higher the bioavailability of an active substance, the more effect it has on the body.

Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Frequently Asked Questions

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.