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90 Capsules Allergen-Free

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250 mg Each of LIPO Berberine

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Serving size 1 capsule

Berberine (Liposomal)

Berberine (Liposomal)

Cardioprotection and metabolism
Regular price $49.95 USD
Sale price $49.95 USD Regular price
Shipping calculated at checkout.

Berberine is a natural compound shown to exert antioxidant and cardioprotective effects.† LIPO Berberine is formulated to support glucose and lipid metabolism, heart health, and overall metabolic homeostasis.†

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90 Capsules Allergen-Free

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250 mg Each of LIPO Berberine

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Serving size 1 capsule

Details

Berberine is a bioactive compound produced in plants and has been appreciated for its health benefits for centuries.† Today, Berberine remains at the forefront of health and wellness research due to its ability to support metabolic health.†

Liposomal Delivery

The efficacy of standard formulations of Berberine is limited due to low absorption and extensive breakdown after ingestion.† A study using liposomal delivery found administration of Liposomal Berberine in rats increased retention time in circulation from .42 to 10 hours (23-46x).†

The figure below shows the amount of liposomal Berberine formulations (yellow and orange bars) is higher in tissues and blood compared to a standard formulation (blue bar).

Standard Berberine has poor absorption and hasless than 1%oral bioavailability, meaning its levels in the blood quickly diminish after ingestion.† To address this issue, LIPO Berberine uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†

View full details

Berberine is a bioactive compound produced in plants and has been appreciated for its health benefits for centuries.† Today, Berberine remains at the forefront of health and wellness research due to its ability to support metabolic health.†

Liposomal Delivery of Berberine


Standard Berberine has poor absorption and hasless than 1%oral bioavailability, meaning its levels in the blood quickly diminish after ingestion.† To address this issue, LIPO Berberine uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†

The efficacy of standard formulations of Berberine is limited due to low absorption and extensive breakdown after ingestion.† A study using liposomal delivery found administration of Liposomal Berberine in rats increased retention time in circulation from .42 to 10 hours (23-46x).†

The figure below shows the amount of liposomal Berberine formulations (yellow and orange bars) is higher in tissues and blood compared to a standard formulation (blue bar).

Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Frequently Asked Questions

LIPOSOMAL DELIVERY

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What’s the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.

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