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90 Capsules Allergen-Free

300 mg Each of LIPO CaAKG

Serving size 1 capsule

CaAKG

Mitochondrial Activation

$48.95 USD

4.3

Rated 4.3 out of 5 stars

10 Reviews

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Support healthy aging, mitochondrial function & metabolic health with CaAKG, the stable form of the naturally occuring substance, Alpha-Ketoglutarate (AKG), which declines as you age.

Each 300 mg capsule of CaAKG is comprised of 60 mg Calcium and 240 mg AKG.

LIPO CaAKG is also available in our combination product, Defender.

90 Capsules Allergen-Free

300 mg Each of LIPO CaAKG

Serving size 1 capsule

View full details

Feel the Shift—From Cellular Slowness to Systemic Strength

If you're doing everything right—eating well, staying active, optimizing sleep—but still feel like your body isn't keeping up, the problem may be happening deeper than diet. Your cells are losing momentum.

Alpha-ketoglutarate (AKG) is a critical molecule for energy metabolism, detoxification, and cellular resilience. It declines sharply with age. Without it, your mitochondria work less efficiently, your metabolism slows, and your ability to bounce back fades.

LIPO CaAKG is designed to restore that missing momentum—directly at the cellular level.

What it does for you

Boosts mitochondrial energy output — fuels the Krebs cycle, your body’s ATP-generating engine

Buffers cellular stress — supports the clearance of age-related metabolic waste

Supports calcium signaling — key to bone health and cellular repair

Promotes metabolic balance — helps your body adapt to aging without chaos

Liposomal delivery for advanced bioavailability — protected, targeted deliveryn where it counts

Why Calcium-AKG?

You’ve heard of NAD+. You might even be taking it.

But AKG works upstream—feeding the very cycle that NAD+ fuels. It’s a key player in the Krebs cycle, where energy is made and aging is managed.

Binding AKG to calcium improves its stability and delivers dual benefits: energy production + calcium signaling, essential for bones, muscles, and cellular coordination.

Without enough AKG, your cells slow down. With it, they stay sharp, efficient, and adaptable.

Most AKG supplements fall apart before they reach the bloodstream. Ours don’t.

LIPO CaAKG uses dry liposomal encapsulation—a delivery system that protects each molecule from stomach acid and digestive enzymes, then shuttles it directly into your cells using phospholipid spheres that mimic your own membranes.

The result: up to 5x better absorption, with fewer capsules and more consistent results.

This Formula is for You If You’re Looking To:

Restore cellular energy without stimulants
Support healthy aging from the inside out
Help your body detoxify metabolic byproducts more efficiently
Fortify long-term metabolic health and bone density
Maintain stamina, clarity, and resilience as you age

CaAKG

Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

CaAKG COA p1

Open Certification

CaAKG COA p2

Open Certification

Frequently Asked Questions

LIPOSOMAL DELIVERY

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.

FW
Frank W.
Verified Buyer
I recommend this product
Rated 5 out of 5 stars
2 months ago
It is one of the now many longevity compound shown to enhance longevity
It is one of the now many longevity compound shown to enhance longevity, and liposomal is le best uptake strategy for getting it into cells.
Was this helpful?
CV
Chuck V.
Verified Buyer
Rated 3 out of 5 stars
1 week ago
New to this product
I'vealways been very pleased and happy with products from Renue by Science. I'm not sure what to expect from CaAGC. I haven't been on it very long.I'm70 y.o. and noticing loss of muscle mass which is one reason I started taking it. I do trust the science behind it and appreciate the information provided with all of the products.
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MG
Matt~618 G. o. Y.
Verified Buyer
I recommend this product
Rated 5 out of 5 stars
2 weeks ago
5 Stars
Great longevity supplements in my stack
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MH
Matthew Hoffman
I recommend this product
Rated 5 out of 5 stars
2 weeks ago
5 Stars
Great longevity supplements in my stack
Was this helpful?
BC
Brian C.
I recommend this product
Rated 5 out of 5 stars
4 months ago
I definitely felt a difference after taking it on the second day
I definitely felt a difference after taking it on the second day. The research I completed on how RBS formulates their liposomal products confirms it is of the Highest Quality.
Was this helpful?

NMN Pure Powder

NAD+ Complete

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NMNs Fast Dissolve Tabs

CaAKG

CaAKG

Mitochondrial Activation

Feel the Shift—From Cellular Slowness to Systemic Strength

LIPO CaAKG is designed to restore that missing momentum—directly at the cellular level.

What it does for you

Why Calcium-AKG?

Most AKG supplements fall apart before they reach the bloodstream. Ours don’t.

This Formula is for You If You’re Looking To:

CaAKG

Certifications

Supported by Science

Purest Ingredients

Advanced Testing

Certified Labs

CaAKG COA p1

CaAKG COA p2

LIPOSOMAL DELIVERY

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