Supplement bottle labeled 'Lipo Spermidine' by Renue on a reflective surface with a dark background
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90 Capsules Allergen-Free

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Serving Size 2 Capsules

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- alternative_title: Spermidine
- byline: Cellular Renewal
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- coa_test_date: 2023-05-11
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- delivery_mechanism: liposomal, capsule
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- servings_per_container: 45
- specification: 90 Capsules
- stacking_rationale: NAD+ Complete (NAD+ restoration + autophagy synergy), EGCG Green Tea (mitophagy + mitochondrial quality control), Quercetin (CD38 inhibition + complementary cellular maintenance), Restore PM (nighttime autophagy amplification)
- testing_lab: Micro Quality Labs Inc
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Spermidine

Spermidine

Cellular Renewal

$49.95 USD
$49.95 USD
4.9
Rated 4.9 out of 5 stars
19 Reviews
Shipping calculated at checkout.

Spermidine has the unique ability to activate autophagy, a powerful anti-aging process that lowers systemic inflammation & preserves NAD⁺ levels.

LIPO Spermidine is also available in our combination product, Senolytique.

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90 Capsules Allergen-Free

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Serving Size 2 Capsules

View full details

Spermidine has been studied for a range of health-protective effects that promote healthy aging and longevity.

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What is Spermidine?

Spermidine is a naturally occurring molecule that is vital to cell function and survival. It’s part of a group of molecules called polyamines. Declining polyamine levels are associated with inflammation-driven aging.

Many studies have shown the potential health benefits of Resveratrol: 

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Liposomal Spermidine

Although a powerful compound, Spermidine is well known for having poor bioavailability. To address this issue, LIPO Spermidine uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†

Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream. (1)

This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.

Spermidine

Spermidine

Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Spermidine Heavy Metal COA 03-26

Spermidine Heavy Metal COA 03-26

Open Certification
Spermidine Microb COA 03-26

Spermidine Microb COA 03-26

Open Certification
spermidine_report-3_v1

spermidine_report-3_v1

Open Certification

Frequently Asked Questions

LIPOSOMAL DELIVERY

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.

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4.9
Rated 4.9 out of 5 stars
Based on 19 reviews
Total 5 star reviews: 18 Total 4 star reviews: 1 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
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19 reviews
  • DR
    David R.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Very noticeable difference

    Very noticeable difference in cognition when not taken. Great product.

    Was this helpful?
  • NT
    N T.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Great Product

    Great product, quick delivery!

    Was this helpful?
  • JG
    Joseph G.
    Flag of Canada
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    1 month ago
    It has been a week in supplementing

    It has been a week in supplementing with spermidine. Satisfied so far though I am aiming to consider benefits over 3 months.

    Was this helpful?
  • RS
    Rick S.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    I like what the product offers and the fact it is Liposomal

    I like what the product offers and the fact it is Liposomal. As it is with most of these anti aging related products it's impossible to tell if it is working when you are taking many other supplements. Overall things seemed to be working. I look nowhere close to 67 and athletically can perform with the very best.

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  • B
    Bryan
    Flag of United States
    I recommend this product
    Rated 5 out of 5 stars
    7 months ago
    Very effective

    Love this spermidine supplement! After taking it for several months, I bumped into two people I hadn't seen in over a year. Both of them said, "You look younger!" I don't take spermidine or anything for the purpose of having a younger appearance, but it's not surprising it seemed to have that effect. Removing poorly functioning and senescent cells makes the body healthier systemically, so it stands to reason that would reflect in one's appearance. Highly recommended!

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