Research

Resveratrol and NMN Restore Brain Metabolism an...
Key Points Wood smoke impaired brain chemistry and behavior Resveratrol + NMN provided the strongest protection Combination therapies showed mixed results NAD+ proved to be a key target for protecting...
Resveratrol and NMN Restore Brain Metabolism an...
Key Points Wood smoke impaired brain chemistry and behavior Resveratrol + NMN provided the strongest protection...

NMN Outperforms NR and Other NAD+ Precursors in...
Key Points NMN outperformed NR and NAM, triggering stronger skin cell protection Cellular aging slowed through improved energy and repair activity Mitochondrial health and energy production were preserved Collagen production...
NMN Outperforms NR and Other NAD+ Precursors in...
Key Points NMN outperformed NR and NAM, triggering stronger skin cell protection Cellular aging slowed through...

The Complete Guide to Choosing Your Optimal NM...
NAD+ Decline: Why Supplementation Matters NAD+ is a critical coenzyme in hundreds of cellular processes, including energy production (glycolysis, citric acid cycle, oxidative phosphorylation), DNA repair through PARP activation, sirtuin-mediated...
The Complete Guide to Choosing Your Optimal NM...
NAD+ Decline: Why Supplementation Matters NAD+ is a critical coenzyme in hundreds of cellular processes, including...

NMN Improves Movement and Brain Health in a Par...
Key Points: NMN restored NAD+ levels and improved motor performance in Parkinsonβs disease (PD) model mice. It reduced inflammation, prevented synaptic loss, and lowered harmful brain immune activity (gliosis). The...
NMN Improves Movement and Brain Health in a Par...
Key Points: NMN restored NAD+ levels and improved motor performance in Parkinsonβs disease (PD) model mice....

Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have been leading choices for raising NAD+ levels. Their popularity stems from the limitations of...
Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have...

Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects βThe aim of this study was to confirm the safety of our manufactured NMN...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...

NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...

NMN Reversed Age-Related Metabolic Dysfunction ...
Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced The metabolism of inflammatory fats was alteredΒ Study Overview Aging was modeled in mice...
NMN Reversed Age-Related Metabolic Dysfunction ...
Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced...

NMN Protects Against Skin Damage in Mouse Study
Key Points Researchers found that NMN offers several important benefits for skin exposed to UVB: Helped maintain healthy skin structure after UVB exposure Reduced inflammation and oxidative stress Supported liver...
NMN Protects Against Skin Damage in Mouse Study
Key Points Researchers found that NMN offers several important benefits for skin exposed to UVB: Helped...

Liposomal NMN Outperforms Standard NMN in Healt...
Key Points Liposomal encapsulation allows NMN to enter cells directly, without relying on transporters or conversion to NR Liposomal NMN significantly increased NAD+ levels by 83% in 4 weeks Liposomal...
Liposomal NMN Outperforms Standard NMN in Healt...
Key Points Liposomal encapsulation allows NMN to enter cells directly, without relying on transporters or conversion...

NMN Transporters and eNAMPT: Key Regulators of ...
βWith these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is now proposed, featuring multi-layered feedback loops mediated by NMN and eNAMPT for mammalian aging...
NMN Transporters and eNAMPT: Key Regulators of ...
βWith these exciting developments, the further reformulated version of the concept, the NAD World 3.0, is...

NMN Rejuvenates Skin in Aging Mice
NMN treatment effectively revitalized aging skin in mice, enhancing both its visible appearance and underlying molecular structure.
NMN Rejuvenates Skin in Aging Mice
NMN treatment effectively revitalized aging skin in mice, enhancing both its visible appearance and underlying molecular...