Research

600 mg of NMN Improves Endurance In People Aged...
A study published on April 11, 2022 claims that 600 mg of NMN improves strength, well-being and the biological age in people aged 40-65. This study confirms NMN supplementation increases...
600 mg of NMN Improves Endurance In People Aged...
A study published on April 11, 2022 claims that 600 mg of NMN improves strength, well-being...

Inhibition of CD38 Increases NAD+ Levels
Inhibition of CD38 Increases NAD+ and Extends Lifespan and Healthspan Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant...
Inhibition of CD38 Increases NAD+ Levels
Inhibition of CD38 Increases NAD+ and Extends Lifespan and Healthspan Two recent studies have found that...

NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels (right graph). Dr. David Sinclair is a co-founder of...
NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice...

Why Dr. Sinclair takes NMN instead of NR
βNMN makes mice run further. Old mice can run 50% further, because they have better blood flow, better energy. NR at the same dose did not do that. In fact...
Why Dr. Sinclair takes NMN instead of NR
βNMN makes mice run further. Old mice can run 50% further, because they have better blood...

David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field of longevity research. In a recent video, titled βDr David Sinclair β Defeating Ageing...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field...

Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the opposite of what you are trying to accomplish by taking NAD+ boosters. The body...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the...

Reduced Nicotinamide Mononucleotide - A Tale of...
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are both well-known NAD+ precursors that can effectively increase NAD+ levels across multiple tissues. They are very similar to each other. In fact,...
Reduced Nicotinamide Mononucleotide - A Tale of...
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are both well-known NAD+ precursors that can effectively increase...

Study Shows NMN Supplementation or CD38 Inhibit...
Declining NAD+ levels are a major contributor to cardiovascular disease in mice. It was demonstrated that raising NAD+ levels through NMN supplementation or by CD38 inhibition can restore cardiovascular function...
Study Shows NMN Supplementation or CD38 Inhibit...
Declining NAD+ levels are a major contributor to cardiovascular disease in mice. It was demonstrated that...

Bacteria in Gastrointestional Tract Metabolize ...
Several experiments were completed that all measured NAD+ metabolites in the Gastrointestinal Tract (GIT) and Liver, 4 hours after a single dose of either 50mg/kg or 500 mg/kg by oral...
Bacteria in Gastrointestional Tract Metabolize ...
Several experiments were completed that all measured NAD+ metabolites in the Gastrointestinal Tract (GIT) and Liver,...

CD73 utilization shows importance of NMN to res...
Like prior studies (1), they found that this transport method did not impede NMN from entering cells, as NR and NMN performed equally at restoring NAD+. They also determined that...
CD73 utilization shows importance of NMN to res...
Like prior studies (1), they found that this transport method did not impede NMN from entering...

Case Study on Liposomal NMN Shows Positive Impa...
βIn an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme...
Case Study on Liposomal NMN Shows Positive Impa...
βIn an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited...

1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing...