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Scientific Evidence Library
Nicotinamide Riboside Repaired Brain Damage and...
Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage and preserved structure Normalized ATP production and improved energy balance Suppressed brain cell inflammation...
Nicotinamide Riboside Repaired Brain Damage and...
Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage...
Resveratrol and NMN Restore Brain Metabolism an...
Key Points Wood smoke impaired brain chemistry and behavior Resveratrol + NMN provided the strongest protection Combination therapies showed mixed results NAD+ proved to be a key target for protecting...
Resveratrol and NMN Restore Brain Metabolism an...
Key Points Wood smoke impaired brain chemistry and behavior Resveratrol + NMN provided the strongest protection...
NMN Improves Movement and Brain Health in a Par...
Key Points: NMN restored NAD+ levels and improved motor performance in Parkinson’s disease (PD) model mice. It reduced inflammation, prevented synaptic loss, and lowered harmful brain immune activity (gliosis). The...
NMN Improves Movement and Brain Health in a Par...
Key Points: NMN restored NAD+ levels and improved motor performance in Parkinson’s disease (PD) model mice....
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...
Trigonelline Improves Healing and Reduces Damag...
“Trigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme complexes, and modulating apoptotic and neurotrophic factors.”
Trigonelline Improves Healing and Reduces Damag...
“Trigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme...
NMN Enhanced Mitochondrial Stress Response and ...
“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by which NAD+-boosting agent nicotinamide mononucleotide (NMN) regulates MSR in AD models.”
NMN Enhanced Mitochondrial Stress Response and ...
“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by...
NMN Offers More Protection Than NR in Friedreic...
Key Points: NMN and NR provided several benefits in mice with FRDA and highlighted key differences between the two treatments: NMN more effectively restored NAD+ levels in the heart than...
NMN Offers More Protection Than NR in Friedreic...
Key Points: NMN and NR provided several benefits in mice with FRDA and highlighted key differences...
NMN Enhances Cellular Protection and Cognitive ...
Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory Reduced neuronal injury Promoted clearance of abnormal tau protein Activated autophagy Enhanced antioxidant defense...
NMN Enhances Cellular Protection and Cognitive ...
Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory...
Berberine Improves Motor Function in a Rat Mode...
Key Points: Berberine supplementation displayed therapeutic benefits for managing Parkinson’s disease symptoms: Improved motor function and coordination Reduced oxidative stress and enhanced antioxidant defenses Restored mitochondrial function Decreased neuroinflammation and...
Berberine Improves Motor Function in a Rat Mode...
Key Points: Berberine supplementation displayed therapeutic benefits for managing Parkinson’s disease symptoms: Improved motor function and...
NMN Nanoparticles Outperform Free NMN for Anti-...
This study investigated the potential of NMN-loaded nanoparticles to prevent age-related decline in a model of aging mice.
NMN Nanoparticles Outperform Free NMN for Anti-...
This study investigated the potential of NMN-loaded nanoparticles to prevent age-related decline in a model of...
EGCG Injection from Green Tea Protects Brain Ce...
EGCG showed several benefits in mice with damaged neurons: Reduced anxiety-like behaviors and motor impairment Reduced degeneration of key brain cells controlling movement Lowered accumulation of harmful proteins linked to...
EGCG Injection from Green Tea Protects Brain Ce...
EGCG showed several benefits in mice with damaged neurons: Reduced anxiety-like behaviors and motor impairment Reduced...
Liposomal delivery of NR shows increased bioava...
"Liposome-based NR loading is an effective strategy for improving the pharmacokinetics and bioavailability of NR, especially to the brain."
Liposomal delivery of NR shows increased bioava...
"Liposome-based NR loading is an effective strategy for improving the pharmacokinetics and bioavailability of NR, especially...