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Scientific Evidence Library
Urolithin A Improves Muscle Strength and E...
Key Points Urolithin A improved lower-body muscle strength. Higher doses improved aerobic endurance and walking performance. Benefits appeared to affect on muscle function and quality rather than muscle size. Blood...
Urolithin A Improves Muscle Strength and Exerci...
Key Points Urolithin A improved lower-body muscle strength. Higher doses improved aerobic endurance and walking performance....
NMN Preserves Retinal Thickness in Older A...
Key Points NMN helped maintain thickness in a specific area of the retina Placebo group lost retinal thickness in that area, NMN stayed more stable Only one retinal area measured...
NMN Preserves Retinal Thickness in Older Adults
Key Points NMN helped maintain thickness in a specific area of the retina Placebo group lost...
New Human Data Is Reshaping What We Know A...
The βAge-Related NADβΊ Declineβ Model Is Being Revisited Early human studies helped build the case for age-related NADβΊ decline. Lower NADβΊ levels in older adults were found using blood metabolomics....
New Human Data Is Reshaping What We Know About ...
The βAge-Related NADβΊ Declineβ Model Is Being Revisited Early human studies helped build the case for...
NR + Exercise Improves Fitness in Friedrei...
Β Key Points Combination improved heart and lung fitness NR alone increased NAD+ levels Exercise improved performance Benefits appear to be driven by improved energy utilization Methods Sixty-six adults and...
NR + Exercise Improves Fitness in Friedreichβs ...
Β Key Points Combination improved heart and lung fitness NR alone increased NAD+ levels Exercise improved...
Ashwagandha Boosts Testosterone in Aging Men
Key Points Ashwagandha increased DHEA-S by 18% Testosterone saw a 14.7% increase Cortisol and estradiol levels were not significantly affected Boosts decreased after people stopped taking ashwagandha The intervention was...
Ashwagandha Boosts Testosterone in Aging Men
Key Points Ashwagandha increased DHEA-S by 18% Testosterone saw a 14.7% increase Cortisol and estradiol levels...
Melatonin Improves Skin and Sleep Quality
Key Points Melatonin significantly reduced eczema severity Itch intensity and overall discomfort decreased Sleep quality, falling asleep, and staying asleep improved Quality of life scores increased after 4 weeks Overview...
Melatonin Improves Skin and Sleep Quality
Key Points Melatonin significantly reduced eczema severity Itch intensity and overall discomfort decreased Sleep quality, falling...
NMN Supports Healthy Blood Pressure in Adu...
Key Points NMN significantly reduced diastolic blood pressure (DBP) Systolic blood pressure (SBP) showed a non-significant reduction Adults 60+ saw a ~4 mmHg reduction in SBP NMN was well tolerated,...
NMN Supports Healthy Blood Pressure in Adults: ...
Key Points NMN significantly reduced diastolic blood pressure (DBP) Systolic blood pressure (SBP) showed a non-significant...
NMN & NR Increase NAD+ in Blood and Brain
Key Points NAD+ blood levels steadied after 2 weeks Brain NAD+ increased after 4 weeks Elevated NAD+ declined gradually after stopping "Both NR and NMN showed excellent tolerability with no...
NMN & NR Increase NAD+ in Blood and Brain
Key Points NAD+ blood levels steadied after 2 weeks Brain NAD+ increased after 4 weeks Elevated...
NMN Rescued Brain Aging and Strengthened t...
Key Points NMN improved movement and memory in aging mice Brain inflammation and oxidative stress were reduced Markers of cellular aging and neuronal death declined Mitochondrial signaling (Sirt1/AMPK/PGC-1Ξ±) increased Gut...
NMN Rescued Brain Aging and Strengthened the Gu...
Key Points NMN improved movement and memory in aging mice Brain inflammation and oxidative stress were...
GABA + L-Theanine Improves Sleep Quality
Key Findings Sleep quality scores decrease by 3 points 84% of participants improved by at least 1 point Nearly one-third no longer met criteria for sleep disturbance Wearable sleep recovery...
GABA + L-Theanine Improves Sleep Quality
Key Findings Sleep quality scores decrease by 3 points 84% of participants improved by at least...
PQQ, NMN, and Interoception After Exhausti...
Key Points "Body Listening" was the only interoceptive domain that significantly improved. Combined PQQ + NMN did not outperform PQQ alone. NMN alone did not significantly change interoception. Across all...
PQQ, NMN, and Interoception After Exhaustive Ex...
Key Points "Body Listening" was the only interoceptive domain that significantly improved. Combined PQQ + NMN...
Fisetin Improved Brain Recovery After Stroke
Key Points Fisetin increased good recovery rates from 29% to 41.9% within 24 hours After 7 days, 45.2% of delayed-treatment patients taking fisetin had favorable outcomes Markers of inflammation and...
Fisetin Improved Brain Recovery After Stroke
Key Points Fisetin increased good recovery rates from 29% to 41.9% within 24 hours After 7...