Key Points NMN and NR provided benefits in mice on a high-fat diet (HFD), but NMN offered more significant protection against NAFLD: Both NMN and NR prevented weight gain and...
A recent study investigated the effects of NMN and NR on ovary health and function in middle-aged rats. “This study reveals that NMN alone or NR alone can rebalance mitochondrial...
“We have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed quick, direct NMN uptake into blood circulation and cells.”
This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in patients with Parkinson’s Disease (PD).
Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's time to sleep, wake up, eat, and digest. This study evaluated the effects of...
This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial function in the skeletal muscle.
NR Preserved Intestinal Lining Integrity During Excessive Alcohol Intake “In particular, the intestine, as the main organ of ethanol absorption, is susceptible to serious injury from excess drinking.” When mice...
NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in muscle NAD+ was observed after 7 days of IV administration of NR. Oral administration...
“But until now, it was unknown whether NR reached targeted organs like the brain to have a real therapeutic effect,” according to Christopher Martens, one of the key researchers in...