Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--NMN More Effective Than NR for NAFLD in Mice

NMN More Effective Than NR for NAFLD in Mice

4 min

Key Points NMN and NR provided benefits in mice on a high-fat diet (HFD), but NMN offered more significant protection against NAFLD: Both NMN and NR prevented weight gain and...

4 min

NMN More Effective Than NR for NAFLD in Mice

Key Points NMN and NR provided benefits in mice on a high-fat diet (HFD), but NMN...

article-page-carousel-item--NMN and NR Alleviate Ovarian Aging in Rats

NMN and NR Alleviate Ovarian Aging in Rats

3 min

A recent study investigated the effects of NMN and NR on ovary health and function in middle-aged rats. “This study reveals that NMN alone or NR alone can rebalance mitochondrial...

3 min

NMN and NR Alleviate Ovarian Aging in Rats

A recent study investigated the effects of NMN and NR on ovary health and function in...

article-page-carousel-item--Liposomal delivery of NR shows increased bioavailability

Liposomal delivery of NR shows increased b...

2 min

"Liposome-based NR loading is an effective strategy for improving the pharmacokinetics and bioavailability of NR, especially to the brain."

2 min

Liposomal delivery of NR shows increased bioava...

"Liposome-based NR loading is an effective strategy for improving the pharmacokinetics and bioavailability of NR, especially...

article-page-carousel-item--Enhanced NMN Detection Validates Slc12a8-Dependent Uptake

Enhanced NMN Detection Validates Slc12a8-D...

5 min

“We have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed quick, direct NMN uptake into blood circulation and cells.”

5 min

Enhanced NMN Detection Validates Slc12a8-Depend...

“We have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed...

article-page-carousel-item--High-Dose NR is Safe & Does Not Deplete Methyl Pools in PD Trial

High-Dose NR is Safe & Does Not Deplete Me...

4 min

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in patients with Parkinson’s Disease (PD).

4 min

High-Dose NR is Safe & Does Not Deplete Methyl ...

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in...

article-page-carousel-item--Clinical Trial Fails to Find Significant Benefit of NR in Adults with MCI

Clinical Trial Fails to Find Significant B...

5 min

This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI and effectively increased blood levels of NAD+.

5 min

Clinical Trial Fails to Find Significant Benefi...

This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI...

article-page-carousel-item--NR Regulates the Cardiac Internal Clock of Aged Mice

NR Regulates the Cardiac Internal Clock of...

2 min

Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's time to sleep, wake up, eat, and digest. This study evaluated the effects of...

2 min

NR Regulates the Cardiac Internal Clock of Aged...

Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's...

article-page-carousel-item--Apigenin and Nicotinamide Riboside Target Gouty Inflammation

Apigenin and Nicotinamide Riboside Target ...

2 min

This study evaluated the effects of Apigenin and Nicotinamide Riboside (NR) on factors associated with gouty arthritis.

2 min

Apigenin and Nicotinamide Riboside Target Gouty...

This study evaluated the effects of Apigenin and Nicotinamide Riboside (NR) on factors associated with gouty...

article-page-carousel-item--Study Shows NR Improves Glucose, Lipids, And Body Composition in Mice On A High-Fat Diet

Study Shows NR Improves Glucose, Lipids, A...

3 min

This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial function in the skeletal muscle. 

3 min

Study Shows NR Improves Glucose, Lipids, And Bo...

This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial...

article-page-carousel-item--Study Shows NR Protects the Intestine From Damage Caused by Excessive Alcohol Intake

Study Shows NR Protects the Intestine From...

2 min

NR Preserved Intestinal Lining Integrity During Excessive Alcohol Intake “In particular, the intestine, as the main organ of ethanol absorption, is susceptible to serious injury from excess drinking.” When mice...

2 min

Study Shows NR Protects the Intestine From Dama...

NR Preserved Intestinal Lining Integrity During Excessive Alcohol Intake “In particular, the intestine, as the main...

article-page-carousel-item--Study Shows NR Injections Increase Muscle NAD+ in Mice, Oral Supplementation Does Not

Study Shows NR Injections Increase Muscle ...

2 min

NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in muscle NAD+ was observed after 7 days of IV administration of NR. Oral administration...

2 min

Study Shows NR Injections Increase Muscle NAD+ ...

NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in...

article-page-carousel-item--Study Finds NR Reaches the Brain & Improves Neuron Function

Study Finds NR Reaches the Brain & Improve...

2 min

“But until now, it was unknown whether NR reached targeted organs like the brain to have a real therapeutic effect,” according to Christopher Martens, one of the key researchers in...

2 min

Study Finds NR Reaches the Brain & Improves Neu...

“But until now, it was unknown whether NR reached targeted organs like the brain to have...