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Scientific Evidence Library
NAD+ and Brain Health: Neuroprotective Mechanis...
Nicotinamide adenine dinucleotide (NAD+) has become one of the most buzzworthy supplements on the market, thanks to its powerful neuroprotective properties and potential to boost brain health. In fact, NAD+...
NAD+ and Brain Health: Neuroprotective Mechanis...
Nicotinamide adenine dinucleotide (NAD+) has become one of the most buzzworthy supplements on the market, thanks...
Nicotinamide Riboside Repaired Brain Damage and...
Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage and preserved structure Normalized ATP production and improved energy balance Suppressed brain cell inflammation...
Nicotinamide Riboside Repaired Brain Damage and...
Key Points NR treatment increased brain NAD⁺ and NMN levels. Enhanced memory performance Reduced mitochondrial damage...
NAD+ Accelerates Hearing Recovery
Key Points NAD+ led to greater hearing improvement and faster recovery Average hearing gain nearly doubled: +40.2 dB HL vs +23.1 dB HL (Hearing Levels) Word Recognition Score (WRS) reached...
NAD+ Accelerates Hearing Recovery
Key Points NAD+ led to greater hearing improvement and faster recovery Average hearing gain nearly doubled:...
NAD+ Therapy Improves Cardiovascular Function i...
Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased NAD+ was well tolerated for heart disease patients Methods 180 adults with heart failure...
NAD+ Therapy Improves Cardiovascular Function i...
Key Points NAD+ increased heart function Stress markers and functional status improved Hospitalizations and complications decreased...
Liposomal NAD+ Enhances Delivery and Reduces Ag...
Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7% Decreased key aging markers (p16 and p21) Improved cell survival Delivered 30% more NAD+...
Liposomal NAD+ Enhances Delivery and Reduces Ag...
Key Points Boosted NAD+ in human blood vessel cells Reduced cellular aging (senescent cells) by 28.7%...
NMN Outperforms NR and Other NAD+ Precursors in...
Key Points NMN outperformed NR and NAM, triggering stronger skin cell protection Cellular aging slowed through improved energy and repair activity Mitochondrial health and energy production were preserved Collagen production...
NMN Outperforms NR and Other NAD+ Precursors in...
Key Points NMN outperformed NR and NAM, triggering stronger skin cell protection Cellular aging slowed through...
Emerging Strategies, Applications, and Challeng...
Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a master regulator of health, supporting DNA repair, epigenetic programming, immune responses, and mitochondrial function....
Emerging Strategies, Applications, and Challeng...
Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects “The aim of this study was to confirm the safety of our manufactured NMN...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers,...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging...
A Novel NAD+ Precursor (NRH) Improves Glucose a...
“To our knowledge, this is the first report showing that NRH can reach multiple tissues intact and provide a broad spectrum of effects through potent NAD+ enhancement and subsequent SIRT...
A Novel NAD+ Precursor (NRH) Improves Glucose a...
“To our knowledge, this is the first report showing that NRH can reach multiple tissues intact...
Increased NAD+ Turnover, Minor Decline in Level...
“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation, supporting the rationale for NAD+ augmentation to attenuate disease severity.”
Increased NAD+ Turnover, Minor Decline in Level...
“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation,...