Scientific Evidence Library

article-page-carousel-item--High-Dose NR is Safe & Does Not Deplete Methyl Pools in PD Trial

High-Dose NR is Safe & Does Not Deplete Methyl ...

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in patients with Parkinson’s Disease (PD).

High-Dose NR is Safe & Does Not Deplete Methyl ...

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in...

article-page-carousel-item--Clinical Trial Fails to Find Significant Benefit of NR in Adults with MCI

Clinical Trial Fails to Find Significant Benefi...

This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI and effectively increased blood levels of NAD+.

Clinical Trial Fails to Find Significant Benefi...

This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI...

article-page-carousel-item--NMN Enhanced HIV-1 Therapy in Mice

NMN Enhanced HIV-1 Therapy in Mice

β€œResults from the humanized mouse study demonstrated that NMN treatment could improve the therapeutic effect of cART in vivo on reconstituting CD4+ T cells and improving CD4/CD8 ratio significantly over...

NMN Enhanced HIV-1 Therapy in Mice

β€œResults from the humanized mouse study demonstrated that NMN treatment could improve the therapeutic effect of...

article-page-carousel-item--Efficacy and Safety of NAD+ Precursors in Clinical Trials

Efficacy and Safety of NAD+ Precursors in Clini...

A recent systematic review evaluated ten studies with NAD+ precursors for efficacy and safety.

Efficacy and Safety of NAD+ Precursors in Clini...

A recent systematic review evaluated ten studies with NAD+ precursors for efficacy and safety.

article-page-carousel-item--Deep Sleep May Protect Against Dementia

Deep Sleep May Protect Against Dementia

β€œThese data from a community-based sample demonstrate that SWS percentage declines over time in adults 60 years and older and that greater declines are associated with the risk of future...

Deep Sleep May Protect Against Dementia

β€œThese data from a community-based sample demonstrate that SWS percentage declines over time in adults 60...

article-page-carousel-item--NR Regulates the Cardiac Internal Clock of Aged Mice

NR Regulates the Cardiac Internal Clock of Aged...

Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's time to sleep, wake up, eat, and digest. This study evaluated the effects of...

NR Regulates the Cardiac Internal Clock of Aged...

Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's...

article-page-carousel-item--Apigenin and Nicotinamide Riboside Target Gouty Inflammation

Apigenin and Nicotinamide Riboside Target Gouty...

This study evaluated the effects of Apigenin and Nicotinamide Riboside (NR) on factors associated with gouty arthritis.

Apigenin and Nicotinamide Riboside Target Gouty...

This study evaluated the effects of Apigenin and Nicotinamide Riboside (NR) on factors associated with gouty...

article-page-carousel-item--Confirmation NMN enters some cells directly

Confirmation NMN enters some cells directly

A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN uptake and metabolism in cells.Β  Β 

Confirmation NMN enters some cells directly

A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN...

article-page-carousel-item--Novel Delivery System Improves NMN Absorption in Mice

Novel Delivery System Improves NMN Absorption i...

β€œUpon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

Novel Delivery System Improves NMN Absorption i...

β€œUpon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN,...

article-page-carousel-item--NMN Reduces Heart Failure and Extends Lifespan in Mice

NMN Reduces Heart Failure and Extends Lifespan ...

β€œThese results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”

NMN Reduces Heart Failure and Extends Lifespan ...

β€œThese results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32...

article-page-carousel-item--Quercetin Prevents Bone Loss and Preserves Cartilage in Rats

Quercetin Prevents Bone Loss and Preserves Cart...

This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing inflammation and modulating levels of proteins associated with cartilage health.

Quercetin Prevents Bone Loss and Preserves Cart...

This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing...

article-page-carousel-item--NMN Improves Blood Pressure in Humans with Hypertension

NMN Improves Blood Pressure in Humans with Hype...

β€œOverall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic...

NMN Improves Blood Pressure in Humans with Hype...

β€œOverall, the present study may shed new light on novel strategies in which NAD+ boosting therapy,...