Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--Confirmation NMN enters some cells directly

Confirmation NMN enters some cells directly

2 min

A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN uptake and metabolism in cells.   

2 min

Confirmation NMN enters some cells directly

A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN...

article-page-carousel-item--Novel Delivery System Improves NMN Absorption in Mice

Novel Delivery System Improves NMN Absorpt...

4 min

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

4 min

Novel Delivery System Improves NMN Absorption i...

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN,...

article-page-carousel-item--NMN Reduces Heart Failure and Extends Lifespan in Mice

NMN Reduces Heart Failure and Extends Life...

3 min

“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32 cardiomyocyte–specific knockout mice, thereby prolonging their lifespan.”

3 min

NMN Reduces Heart Failure and Extends Lifespan ...

“These results suggest that NMN treatment functionally ameliorated or prevented exacerbation of heart failure in p32...

article-page-carousel-item--Quercetin Prevents Bone Loss and Preserves Cartilage in Rats

Quercetin Prevents Bone Loss and Preserves...

5 min

This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing inflammation and modulating levels of proteins associated with cartilage health.

5 min

Quercetin Prevents Bone Loss and Preserves Cart...

This study showed that Quercetin protected rats with osteoarthritis against bone and cartilage damage by reducing...

article-page-carousel-item--NMN Improves Blood Pressure in Humans with Hypertension

NMN Improves Blood Pressure in Humans with...

5 min

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy, including NMN supplement and CD38 inhibition, may turn out to be a promising therapeutic...

5 min

NMN Improves Blood Pressure in Humans with Hype...

“Overall, the present study may shed new light on novel strategies in which NAD+ boosting therapy,...

article-page-carousel-item--Study Shows NR Improves Glucose, Lipids, And Body Composition in Mice On A High-Fat Diet

Study Shows NR Improves Glucose, Lipids, A...

3 min

This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial function in the skeletal muscle. 

3 min

Study Shows NR Improves Glucose, Lipids, And Bo...

This study showed that NR supplementation protected mice from HFD-induced metabolic dysfunction, specifically through protecting mitochondrial...

article-page-carousel-item--Apigenin Balances the Gut Microbiome and Improves Ulcerative Colitis in Mice

Apigenin Balances the Gut Microbiome and I...

5 min

This study examined the effects of Apigenin on inflammation, gut barrier integrity, and the gut microbiome in mice with ulcerative colitis (UC). 

5 min

Apigenin Balances the Gut Microbiome and Improv...

This study examined the effects of Apigenin on inflammation, gut barrier integrity, and the gut microbiome...

article-page-carousel-item--Study Reveals New Technique to Quickly and Accurately Measure Blood NAD+ Levels

Study Reveals New Technique to Quickly and...

5 min

Highlights A new technique has been developed to rapidly and effectively measure blood NAD+ levels in humans. Aerobic exercise and NMN supplementation increase NAD+ levels Gender- and age- variations in...

5 min

Study Reveals New Technique to Quickly and Accu...

Highlights A new technique has been developed to rapidly and effectively measure blood NAD+ levels in...

article-page-carousel-item--Palmitoylethanolamide (P.E.A.) Reduces Inflammation and Anxiety in Obese Mice

Palmitoylethanolamide (P.E.A.) Reduces Inf...

4 min

This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation. “As our data demonstrated, the blunted synthesis of pro-inflammatory cytokines by PEA can stop this vicious cycle among...

4 min

Palmitoylethanolamide (P.E.A.) Reduces Inflamma...

This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation. “As our data demonstrated,...

article-page-carousel-item--Anti-Aging Effects of NMN - Human Clinical Trials Review

Anti-Aging Effects of NMN - Human Clinical...

6 min

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

6 min

Anti-Aging Effects of NMN - Human Clinical Tria...

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

article-page-carousel-item--Study Shows Resveratrol Preserves Muscle Health in Aged Mice

Study Shows Resveratrol Preserves Muscle H...

2 min

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

2 min

Study Shows Resveratrol Preserves Muscle Health...

Resveratrol supplementation effectively protected mice against age-related muscle mass loss, heart cell enlargement, and motor dysfunction.

article-page-carousel-item--Study Shows NMN Protects Against Lung Damage in Mice

Study Shows NMN Protects Against Lung Dama...

5 min

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

5 min

Study Shows NMN Protects Against Lung Damage in...

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure...