LIPO Melatonin™ promotes high-quality sleep and balances your “body clock.” Benefits may include improvement of sleep onset, sleep pattern and a decrease in cortisol levels.
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Offering an advanced liposomal source of the natural hormone—N-acetyl-5-methoxytryptamine—LIPO Melatonin™ is expertly designed to overcome low absorption issues.
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Balance Cortisol Levels
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Melatonin is mainly known for its ability to regulate the sleep-wake cycle (circadian rhythm or chronobiology) via its release from the pineal gland. Studies demonstrate that melatonin decreases sleep onset latency, increases total sleep time and improves overall sleep quality. 1
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In addition to improving sleep, melatonin is also involved in managing immune function, blood pressure and cortisol levels. 2
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Only 15% Absorption in Standard Melatonin Supplements
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Oral melatonin has an absolute bioavailability of about 15 percent. So, if you take a 4 mg melatonin pill, your body is only absorbing around 0.6 mg. 3
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Our encapsulation process in liposomes protects melatonin from premature degradation while enhancing its intestinal absorption.
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The absorption of non-liposomal oral melatonin is minimal due to high first-pass clearance in the liver and low absorption in the gastrointestinal tract. 4
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Liposomes extend the time a supplement is available in the bloodstream, but the peak availability is between 2 and 4 hours, which is while you are sleeping.
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However, some is absorbed well before the 2 hours and actually may work faster than standard Melatonin.
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This study found Liposomal Melatonin decreased the time to sleep (Sleep latency – SL). from 18 minutes to 10 minutes.
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“A significant difference in SL was observed (10.8 ± 5 vs. 18.1 ± 13.4 min, p-value = 0.002)… Our study confirmed the efficacy and safety of melatonin administration in sleep induction. Nonetheless, liposomal melatonin presents a greater bioavailability, ensuring a faster effect and allowing lower dosages.”