90 Capsules Allergen-Free

Serving size 1 capsule

P.E.A. - Palmitoylethanolamide (Liposomal)

Name: P.E.A. - Palmitoylethanolamide (Liposomal)
Brand: Renue Store
SKU: 656165996957
Price: 59.95 USD
Availability: InStock

Neuroprotective inflammation support

$59.95 USD

Shipping calculated at checkout.

Palmitoylethanolamide (P.E.A.) is a natural compound shown to exert anti-inflammatory, pain-relieving and neuroprotective effects.† LIPO P.E.A. is designed to support healthy aging, cellular health and homeostasis.†

LIPO P.E.A. is also available in our combination product, Shield.

Product variants

90 Capsules Allergen-Free

Serving size 1 capsule

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Since its discovery, P.E.A. has been the subject of extensive research due to its ability to target multiple pathways in the body. P.E.A. is a natural compound produced by your body in response to cellular damage, and its primary role is to restore balance and promote homeostasis.†

Aging is associated with a widespread loss of homeostasis, contributing to chronic inflammation, compromised immune function, and disruptions in hormone regulation and metabolism.† (1)

P.E.A. helps support the body’s natural healing processes, exerting anti-inflammatory, pain-relieving, and neuroprotective effects.† The therapeutic potential of PEA for pain relief has been an exciting research focus because it targets both pain and inflammation simultaneously.†

Numerous clinical trials have shown the potential benefits of P.E.A., including:

Pain & Inflammation: Research shows that P.E.A. activates receptors in the body that regulate pain and inflammation, potentially lowering pain sensitivity by controlling the inflammatory response.† (1) In an 8-week study in subjects with knee osteoarthritis, P.E.A. supplementation of 300 mg per day resulted in a 40% reduction in pain and stiffness.† (2)

Immune System: P.E.A. possesses anti-inflammatory properties, reducing the production of pro-inflammatory signals and inhibiting the activation of immune cells involved in inflammation.† The beneficial effects of PEA on immune function are documented in over 350 peer-reviewed papers, including animal and human studies.† (3)

Brain: P.E.A. has been shown in studies to exhibit neuroprotective properties on the brain by reducing inflammation, promoting the growth of neurons and by regulating neurotransmitters that impact mood and well-being.† (4)

G.I. Tract: Studies show that P.E.A. may protect the lining of the G.I. tract, alleviate inflammation, and regulate processes like pain perception, gut movement, and digestion.† (3)

A comprehensive review on the potential health benefits of P.E.A. can be found here.

Standard P.E.A. has poor absorption and low bioavailability, and its levels in the blood quickly diminish after ingestion. To address this issue, LIPO P.E.A. uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†

Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Strength and Purity Certification Gold Standard Testing PEA Report

Frequently Asked Questions

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.